THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)

The aim of the study. Highlight the most well-founded knowledge that reflects the dependence of treatment and sedation options for patients in the treatment of intracerebral hemorrhage (ICH). Materials and methods. Literature sources related to the study of the annual number of registered stroke...

Full description

Saved in:
Bibliographic Details
Main Authors: S.N. Gritsenko, L. O. Davyhora, S.I. Vorotintsev
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2022-12-01
Series:Сучасні медичні технології
Subjects:
Online Access:https://zmapo-journal.com/index.php/journal/article/view/245
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846092873754214400
author S.N. Gritsenko
L. O. Davyhora
S.I. Vorotintsev
author_facet S.N. Gritsenko
L. O. Davyhora
S.I. Vorotintsev
author_sort S.N. Gritsenko
collection DOAJ
description The aim of the study. Highlight the most well-founded knowledge that reflects the dependence of treatment and sedation options for patients in the treatment of intracerebral hemorrhage (ICH). Materials and methods. Literature sources related to the study of the annual number of registered stroke cases in the world were analyzed. The vast majority of patients remain permanently disabled, which leads to a decrease in the able-bodied population. An important factor in the development of complications and increased mortality is the high variability and persistent increase in blood pressure (BP). Traditional tactics have a number of disadvantages. At present, there are no clear recommendations for the use of certain antihypertensive drugs, and the optimal numbers to which BP should be lowered are debatable. The results. It has been established that sedation plays an important role in the treatment of intracerebral hemorrhage. In fact, it helps control pain, anxiety, agitation and synchronicity of the patient with the ventilator, and also reduces cerebral metabolic demands and improves the brain's tolerance to secondary damage. However, combinations of drugs for its implementation may differ even in units of the same hospital. Conclusions. Combination therapy of propofol with opioids or dexmedetomidine with opioids is most common. However, the heterogeneity of the data makes it impossible to qualitatively interpret the obtained results. In turn, due to the uncertainty of the unequivocal tactics of analgosedation, the question of the optimal dosage of drugs is open. Thus, the optimal treatment of acute hypertension in patients with VMC remains a therapeutic dilemma and an important part of scientific research. Adequate correction of the variability of systemic hemodynamics and cerebral perfusion with the help of analgosedation is a promising direction in the treatment of ICH.
format Article
id doaj-art-8a908a2496364dffaae3dfcbed716e51
institution Kabale University
issn 2072-9367
language English
publishDate 2022-12-01
publisher Zaporizhzhia State Medical and Pharmaceutical University
record_format Article
series Сучасні медичні технології
spelling doaj-art-8a908a2496364dffaae3dfcbed716e512025-01-02T20:19:08ZengZaporizhzhia State Medical and Pharmaceutical UniversityСучасні медичні технології2072-93672022-12-014(55)617110.34287/MMT.4(55).2022.11245THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)S.N. Gritsenko0L. O. Davyhora1S.I. Vorotintsev2State Institution «Zaporizhzhia Medical Academy of post-graduate education Ministry of Health of Ukraine» Zaporizhzhia, UkraineZaporizhzhia State Medical University, UkraineZaporizhzhia State Medical University, UkraineThe aim of the study. Highlight the most well-founded knowledge that reflects the dependence of treatment and sedation options for patients in the treatment of intracerebral hemorrhage (ICH). Materials and methods. Literature sources related to the study of the annual number of registered stroke cases in the world were analyzed. The vast majority of patients remain permanently disabled, which leads to a decrease in the able-bodied population. An important factor in the development of complications and increased mortality is the high variability and persistent increase in blood pressure (BP). Traditional tactics have a number of disadvantages. At present, there are no clear recommendations for the use of certain antihypertensive drugs, and the optimal numbers to which BP should be lowered are debatable. The results. It has been established that sedation plays an important role in the treatment of intracerebral hemorrhage. In fact, it helps control pain, anxiety, agitation and synchronicity of the patient with the ventilator, and also reduces cerebral metabolic demands and improves the brain's tolerance to secondary damage. However, combinations of drugs for its implementation may differ even in units of the same hospital. Conclusions. Combination therapy of propofol with opioids or dexmedetomidine with opioids is most common. However, the heterogeneity of the data makes it impossible to qualitatively interpret the obtained results. In turn, due to the uncertainty of the unequivocal tactics of analgosedation, the question of the optimal dosage of drugs is open. Thus, the optimal treatment of acute hypertension in patients with VMC remains a therapeutic dilemma and an important part of scientific research. Adequate correction of the variability of systemic hemodynamics and cerebral perfusion with the help of analgosedation is a promising direction in the treatment of ICH.https://zmapo-journal.com/index.php/journal/article/view/245hemorrhagic strokeintensive caresedationanalgesiasystemic hemodynamics
spellingShingle S.N. Gritsenko
L. O. Davyhora
S.I. Vorotintsev
THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
Сучасні медичні технології
hemorrhagic stroke
intensive care
sedation
analgesia
systemic hemodynamics
title THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
title_full THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
title_fullStr THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
title_full_unstemmed THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
title_short THE PLACE OF ANALGOSEDATION IN THE MANAGEMENT OF ACUTE ARTERIAL HYPERTENSION IN PATIENT WITH INTRACEREBRAL HEMORRHAGE (REFERENCES)
title_sort place of analgosedation in the management of acute arterial hypertension in patient with intracerebral hemorrhage references
topic hemorrhagic stroke
intensive care
sedation
analgesia
systemic hemodynamics
url https://zmapo-journal.com/index.php/journal/article/view/245
work_keys_str_mv AT sngritsenko theplaceofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences
AT lodavyhora theplaceofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences
AT sivorotintsev theplaceofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences
AT sngritsenko placeofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences
AT lodavyhora placeofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences
AT sivorotintsev placeofanalgosedationinthemanagementofacutearterialhypertensioninpatientwithintracerebralhemorrhagereferences