LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.

LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.

Natural progression of HIV-1 infection depends on genetic variation in the human major histocompatibility complex (MHC) class I locus, and the CD8+ T cell response is thought to be a primary mechanism of this effect. However, polymorphism within the MHC may also alter innate immune activity against...

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Main Authors: Arman A Bashirova, Enrique Martin-Gayo, Des C Jones, Ying Qi, Richard Apps, Xiaojiang Gao, Patrick S Burke, Craig J Taylor, Jerome Rogich, Steven Wolinsky, Jay H Bream, Priya Duggal, Shehnaz Hussain, Jeremy Martinson, Amy Weintrob, Gregory D Kirk, Jacques Fellay, Susan P Buchbinder, James J Goedert, Steven G Deeks, Florencia Pereyra, John Trowsdale, Mathias Lichterfeld, Amalio Telenti, Bruce D Walker, Rachel L Allen, Mary Carrington, Xu G Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004196&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004196&type=printable

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