CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy

CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy

Abstract T‐cell haematological malignancies progress rapidly and have a high mortality rate and effective treatments are still lacking. Here, we developed a drug delivery system utilizing 293T cell‐derived extracellular vesicles (EVs) modified with an anti‐CD7 single‐chain variable fragment (αCD7/EV...

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Bibliographic Details
Main Authors: Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Journal of Extracellular Vesicles
Subjects:
anti‐CD7 single‐chain variable fragment
Bcl2 siRNA
cytochrome C
extracellular vesicles
T‐cell malignancies
Online Access:https://doi.org/10.1002/jev2.70025
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