Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results
This study aims to describe and evaluate the performance of a new device for magnetic hyperthermia that can produce an alternating magnetic field with adjustable frequency without the need to change capacitors from the resonant bank, as required by other commercial devices. This innovation, among ot...
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| Format: | Article |
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MDPI AG
2024-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/14/22/1848 |
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| author | Teresa Castelo-Grande Paulo A. Augusto Lobinho Gomes Eduardo Calvo Domingos Barbosa |
| author_facet | Teresa Castelo-Grande Paulo A. Augusto Lobinho Gomes Eduardo Calvo Domingos Barbosa |
| author_sort | Teresa Castelo-Grande |
| collection | DOAJ |
| description | This study aims to describe and evaluate the performance of a new device for magnetic hyperthermia that can produce an alternating magnetic field with adjustable frequency without the need to change capacitors from the resonant bank, as required by other commercial devices. This innovation, among others, is based on using a capacitator bank that dynamically adjusts the frequency. To validate the novel system, a series of experiments were conducted using commercial magnetic nanoparticles (MNPs) demonstrating the device’s effectiveness and allowing us to identify new challenges associated with the design of more powerful devices. A computational model was also used to validate the device and to allow us to determine the best system configuration. The results obtained are consistent with those from other studies using the same MNPs but with magnetic hyperthermia commercial equipment, confirming the good performance of the developed device (e.g., consistent SAR values between 1.37 and 10.80 W/gMNP were obtained, and experiments reaching temperatures above 43 °C were also obtained). This equipment offers additional advantages, including being economical, user-friendly, and portable. |
| format | Article |
| id | doaj-art-8a3c6d3a53bb4f6e991b200bbfa19e95 |
| institution | Kabale University |
| issn | 2079-4991 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-8a3c6d3a53bb4f6e991b200bbfa19e952024-11-26T18:16:35ZengMDPI AGNanomaterials2079-49912024-11-011422184810.3390/nano14221848Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary ResultsTeresa Castelo-Grande0Paulo A. Augusto1Lobinho Gomes2Eduardo Calvo3Domingos Barbosa4LEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, PortugalInstitute of Molecular and Cellular Biology of Cancer, CSIC/University of Salamanca (GIR Citómica), 37007 Salamanca, SpainFaculty of Natural Sciences, Engineering and Technologies, Lusófona University of Porto, R. de Augusto Rosa 24, 4000-098 Porto, PortugalCEFT—Center of Study of Phenomena’s of Transport, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, PortugalLEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, PortugalThis study aims to describe and evaluate the performance of a new device for magnetic hyperthermia that can produce an alternating magnetic field with adjustable frequency without the need to change capacitors from the resonant bank, as required by other commercial devices. This innovation, among others, is based on using a capacitator bank that dynamically adjusts the frequency. To validate the novel system, a series of experiments were conducted using commercial magnetic nanoparticles (MNPs) demonstrating the device’s effectiveness and allowing us to identify new challenges associated with the design of more powerful devices. A computational model was also used to validate the device and to allow us to determine the best system configuration. The results obtained are consistent with those from other studies using the same MNPs but with magnetic hyperthermia commercial equipment, confirming the good performance of the developed device (e.g., consistent SAR values between 1.37 and 10.80 W/gMNP were obtained, and experiments reaching temperatures above 43 °C were also obtained). This equipment offers additional advantages, including being economical, user-friendly, and portable.https://www.mdpi.com/2079-4991/14/22/1848magnetic hyperthermiacancer treatmentnanotechnologiesnanomaterialsportable apparatus |
| spellingShingle | Teresa Castelo-Grande Paulo A. Augusto Lobinho Gomes Eduardo Calvo Domingos Barbosa Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results Nanomaterials magnetic hyperthermia cancer treatment nanotechnologies nanomaterials portable apparatus |
| title | Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results |
| title_full | Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results |
| title_fullStr | Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results |
| title_full_unstemmed | Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results |
| title_short | Portable Homemade Magnetic Hyperthermia Apparatus: Preliminary Results |
| title_sort | portable homemade magnetic hyperthermia apparatus preliminary results |
| topic | magnetic hyperthermia cancer treatment nanotechnologies nanomaterials portable apparatus |
| url | https://www.mdpi.com/2079-4991/14/22/1848 |
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