Pretreatment of Ascorbic Acid Inhibits MPTP-Induced Astrocytic Oxidative Stress through Suppressing NF-κB Signaling
Astrocytes are a major constituent of the central nervous system (CNS). Astrocytic oxidative stress contributes to the development of Parkinson’s disease (PD). Maintaining production of antioxidant and detoxification of reactive oxygen and nitrogen species (ROS/RNS) in astrocytes is critical to prev...
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Main Authors: | Xiaokang Zeng, Kai Xu, Ji Wang, Yunqi Xu, Shaogang Qu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2020/8872296 |
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