Maternal probiotic exposure enhances CD8 T cell protective neonatal immunity and modulates offspring metabolome to control influenza virus infection

Maternal probiotic exposure enhances CD8 T cell protective neonatal immunity and modulates offspring metabolome to control influenza virus infection

Maternal gut microbiota composition contributes to the status of the neonatal immune system and could influence the early life higher susceptibility to viral respiratory infections. Using a novel protocol of murine maternal probiotic supplementation, we report that perinatal exposure to Lacticaseiba...

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Bibliographic Details
Main Authors: Clara Valentin, Patricia Brito Rodrigues, Marko Verce, Sandrine Delbauve, Léa La Palombara, Florine Demaret, Justine Allard, Isabelle Salmon, Patrice D. Cani, Arnaud Köhler, Amandine Everard, Véronique Flamand
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
IAV
CD8 T cells
early life
memory response
Lacticaseibacillus rhamnosus
Bifidobacterium
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2442526
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https://www.tandfonline.com/doi/10.1080/19490976.2024.2442526

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