Systemic immune response of burns from the acute to chronic phase

Abstract Immune responses that occur following burn injury comprise a series of reactions that are activated in response to damaged autologous tissues, followed by removal of damaged tissues and foreign pathogens such as invading bacteria, and tissue repair. These immune responses are considered to...

Full description

Saved in:
Bibliographic Details
Main Authors: Akinori Osuka, Ayami Shigeno, Hiroshi Matsuura, Shinya Onishi, Kazuhiro Yoneda
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Acute Medicine & Surgery
Subjects:
Online Access:https://doi.org/10.1002/ams2.976
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Immune responses that occur following burn injury comprise a series of reactions that are activated in response to damaged autologous tissues, followed by removal of damaged tissues and foreign pathogens such as invading bacteria, and tissue repair. These immune responses are considered to be programmed in living organisms. Developments of modern medicine have led to the saving of burned patients who could not be cured previously; however, the programmed response is no longer able to keep up, and various problems have arisen. This paper describes the mechanism of immune response specific to burn injury and the emerging concept of persistent inflammation, immunosuppression, and catabolism syndrome.
ISSN:2052-8817