A case report of comprehensive treatment for primary intraspinal carcinosarcoma
BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwe...
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Frontiers Media S.A.
2025-01-01
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Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/full |
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author | Chang Yan Chao-Jun Zhang Jun-bao Wei Hui-wen Liang Song Qu |
author_facet | Chang Yan Chao-Jun Zhang Jun-bao Wei Hui-wen Liang Song Qu |
author_sort | Chang Yan |
collection | DOAJ |
description | BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwent surgery at initial diagnosis, followed by two courses of radiotherapy due to residual tumor, as part of a comprehensive antitumor treatment. Despite good tumor control, she ultimately died of respiratory failure.DiscussionThis is the first reported case of primary intra dural extramedullary carcinosarcoma, detailing its imaging characteristics, pathological morphology, and treatment process. The tumor was responsive to radiotherapy. The rapid progression of intraspinal carcinosarcoma suggests it may be underdiagnosed or underreported, highlighting the need for more cases for clinical evaluation and treatment strategies. |
format | Article |
id | doaj-art-89c58059487c45278add07dd1cab2232 |
institution | Kabale University |
issn | 2234-943X |
language | English |
publishDate | 2025-01-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Oncology |
spelling | doaj-art-89c58059487c45278add07dd1cab22322025-01-07T06:45:14ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14791931479193A case report of comprehensive treatment for primary intraspinal carcinosarcomaChang Yan0Chao-Jun Zhang1Jun-bao Wei2Hui-wen Liang3Song Qu4Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Pathology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaBackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwent surgery at initial diagnosis, followed by two courses of radiotherapy due to residual tumor, as part of a comprehensive antitumor treatment. Despite good tumor control, she ultimately died of respiratory failure.DiscussionThis is the first reported case of primary intra dural extramedullary carcinosarcoma, detailing its imaging characteristics, pathological morphology, and treatment process. The tumor was responsive to radiotherapy. The rapid progression of intraspinal carcinosarcoma suggests it may be underdiagnosed or underreported, highlighting the need for more cases for clinical evaluation and treatment strategies.https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/fullcarcinosarcomacentral nervous system tumorsradiotherapychemotherapycomprehensive treatmentrare disease |
spellingShingle | Chang Yan Chao-Jun Zhang Jun-bao Wei Hui-wen Liang Song Qu A case report of comprehensive treatment for primary intraspinal carcinosarcoma Frontiers in Oncology carcinosarcoma central nervous system tumors radiotherapy chemotherapy comprehensive treatment rare disease |
title | A case report of comprehensive treatment for primary intraspinal carcinosarcoma |
title_full | A case report of comprehensive treatment for primary intraspinal carcinosarcoma |
title_fullStr | A case report of comprehensive treatment for primary intraspinal carcinosarcoma |
title_full_unstemmed | A case report of comprehensive treatment for primary intraspinal carcinosarcoma |
title_short | A case report of comprehensive treatment for primary intraspinal carcinosarcoma |
title_sort | case report of comprehensive treatment for primary intraspinal carcinosarcoma |
topic | carcinosarcoma central nervous system tumors radiotherapy chemotherapy comprehensive treatment rare disease |
url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/full |
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