A case report of comprehensive treatment for primary intraspinal carcinosarcoma

BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwe...

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Main Authors: Chang Yan, Chao-Jun Zhang, Jun-bao Wei, Hui-wen Liang, Song Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/full
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author Chang Yan
Chao-Jun Zhang
Jun-bao Wei
Hui-wen Liang
Song Qu
author_facet Chang Yan
Chao-Jun Zhang
Jun-bao Wei
Hui-wen Liang
Song Qu
author_sort Chang Yan
collection DOAJ
description BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwent surgery at initial diagnosis, followed by two courses of radiotherapy due to residual tumor, as part of a comprehensive antitumor treatment. Despite good tumor control, she ultimately died of respiratory failure.DiscussionThis is the first reported case of primary intra dural extramedullary carcinosarcoma, detailing its imaging characteristics, pathological morphology, and treatment process. The tumor was responsive to radiotherapy. The rapid progression of intraspinal carcinosarcoma suggests it may be underdiagnosed or underreported, highlighting the need for more cases for clinical evaluation and treatment strategies.
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series Frontiers in Oncology
spelling doaj-art-89c58059487c45278add07dd1cab22322025-01-07T06:45:14ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14791931479193A case report of comprehensive treatment for primary intraspinal carcinosarcomaChang Yan0Chao-Jun Zhang1Jun-bao Wei2Hui-wen Liang3Song Qu4Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Pathology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaDepartment of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, ChinaBackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwent surgery at initial diagnosis, followed by two courses of radiotherapy due to residual tumor, as part of a comprehensive antitumor treatment. Despite good tumor control, she ultimately died of respiratory failure.DiscussionThis is the first reported case of primary intra dural extramedullary carcinosarcoma, detailing its imaging characteristics, pathological morphology, and treatment process. The tumor was responsive to radiotherapy. The rapid progression of intraspinal carcinosarcoma suggests it may be underdiagnosed or underreported, highlighting the need for more cases for clinical evaluation and treatment strategies.https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/fullcarcinosarcomacentral nervous system tumorsradiotherapychemotherapycomprehensive treatmentrare disease
spellingShingle Chang Yan
Chao-Jun Zhang
Jun-bao Wei
Hui-wen Liang
Song Qu
A case report of comprehensive treatment for primary intraspinal carcinosarcoma
Frontiers in Oncology
carcinosarcoma
central nervous system tumors
radiotherapy
chemotherapy
comprehensive treatment
rare disease
title A case report of comprehensive treatment for primary intraspinal carcinosarcoma
title_full A case report of comprehensive treatment for primary intraspinal carcinosarcoma
title_fullStr A case report of comprehensive treatment for primary intraspinal carcinosarcoma
title_full_unstemmed A case report of comprehensive treatment for primary intraspinal carcinosarcoma
title_short A case report of comprehensive treatment for primary intraspinal carcinosarcoma
title_sort case report of comprehensive treatment for primary intraspinal carcinosarcoma
topic carcinosarcoma
central nervous system tumors
radiotherapy
chemotherapy
comprehensive treatment
rare disease
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/full
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