Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy. However, a s...

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Main Authors: Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Annals of Clinical and Translational Neurology
Subjects:
neuromyelitis optica spectrum disorders
NMOSD
rituximab
Online Access:https://doi.org/10.1002/acn3.70095
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