Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia
Abstract Background Despite advancements in Human Immunodeficiency Virus (HIV) treatment and care, undernutrition remains a significant concern, accelerating disease progression and risk of Acquired Immune Deficiency Syndrome (AIDS)-related deaths. The nutritional status of second-line antiretrovira...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12889-024-21274-2 |
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| author | Seteamlak Adane Masresha Atitegeb Abera Kidie Getahun Fentaw Mulaw Fentaw Wassie Feleke Mesfin Wudu Kassaw Tadesse Mamo Dejene Aychew Kassie Gidafie Fassikaw Kebede Bizuneh |
| author_facet | Seteamlak Adane Masresha Atitegeb Abera Kidie Getahun Fentaw Mulaw Fentaw Wassie Feleke Mesfin Wudu Kassaw Tadesse Mamo Dejene Aychew Kassie Gidafie Fassikaw Kebede Bizuneh |
| author_sort | Seteamlak Adane Masresha |
| collection | DOAJ |
| description | Abstract Background Despite advancements in Human Immunodeficiency Virus (HIV) treatment and care, undernutrition remains a significant concern, accelerating disease progression and risk of Acquired Immune Deficiency Syndrome (AIDS)-related deaths. The nutritional status of second-line antiretroviral treatment (SLART) users in Ethiopia has not been thoroughly investigated. So, this study aimed to assess the nutritional status of HIV/AIDS patients who were on SLART and its associated factors in Northern Ethiopia. Methods A retrospective cross-sectional study was conducted on 366 HIV-infected adults who had been on SLART for at least six months in northern Ethiopia. Clients who had documented Weight and height at six months of therapy were included. Data was entered and cleaned by using EpiDATA version 4.6.0.2 and statistical analysis was done by STATA version 17. Multiple imputation method was applied to manage variables having up to 25% missing values by using R-Version 3.6.2 software. Binary logistic regression was used with P < 0.05 as a significant predictor in the final analysis. Data was collected from February 01 to April 30, 2021. Results The magnitude of undernutrition among adults who were on SLART in the study area was 38.52% (95%CI: 33.65–43.64). Those populations also had a baseline undernutrition status of 39.1% (95%CI: 34.11–44.15) during their transition to SLART. The risk of being malnourished at six months of SLART initiation was fifteen times higher among those who were undernourished at SLART start (AOR:15.099, 95%CI: 8.532, 26.720) reflecting the high burden of the problem in the advanced courses of HIV/AIDS treatment and care. Conclusions The proportion of undernutrition among SLART users in Northern Ethiopia is high. During HIV therapy, a client’s overall nutritional health is predicted by their prior undernutrition condition. This highlights the need for comprehensive nutritional assessment, counseling, and monitoring of the nutritional status of SLART users in the area with emphasis on an early identification of possible barriers to the improvement of such conditions. Promoting the consumption of nutrient-dense local foods and appropriate food preparation methods in addition to nutritional support are vital in this setting. |
| format | Article |
| id | doaj-art-89667e99a5ea481facaad2d31853b17c |
| institution | Kabale University |
| issn | 1471-2458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | BMC Public Health |
| spelling | doaj-art-89667e99a5ea481facaad2d31853b17c2025-01-12T12:43:17ZengBMCBMC Public Health1471-24582025-01-012511810.1186/s12889-024-21274-2Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern EthiopiaSeteamlak Adane Masresha0Atitegeb Abera Kidie1Getahun Fentaw Mulaw2Fentaw Wassie Feleke3Mesfin Wudu Kassaw4Tadesse Mamo Dejene5Aychew Kassie Gidafie6Fassikaw Kebede Bizuneh7Department of Public Health, Woldia UniversityDepartment of Public Health, Woldia UniversityDepartment of Public Health, Woldia UniversityDepartment of Public Health, Woldia UniversityDepartment of Nursing, Woldia UniversityDepartment of Public Health, Debre Berhan UniversityDepartment of Nursing, Woldia UniversityDepartment of Public Health, Woldia UniversityAbstract Background Despite advancements in Human Immunodeficiency Virus (HIV) treatment and care, undernutrition remains a significant concern, accelerating disease progression and risk of Acquired Immune Deficiency Syndrome (AIDS)-related deaths. The nutritional status of second-line antiretroviral treatment (SLART) users in Ethiopia has not been thoroughly investigated. So, this study aimed to assess the nutritional status of HIV/AIDS patients who were on SLART and its associated factors in Northern Ethiopia. Methods A retrospective cross-sectional study was conducted on 366 HIV-infected adults who had been on SLART for at least six months in northern Ethiopia. Clients who had documented Weight and height at six months of therapy were included. Data was entered and cleaned by using EpiDATA version 4.6.0.2 and statistical analysis was done by STATA version 17. Multiple imputation method was applied to manage variables having up to 25% missing values by using R-Version 3.6.2 software. Binary logistic regression was used with P < 0.05 as a significant predictor in the final analysis. Data was collected from February 01 to April 30, 2021. Results The magnitude of undernutrition among adults who were on SLART in the study area was 38.52% (95%CI: 33.65–43.64). Those populations also had a baseline undernutrition status of 39.1% (95%CI: 34.11–44.15) during their transition to SLART. The risk of being malnourished at six months of SLART initiation was fifteen times higher among those who were undernourished at SLART start (AOR:15.099, 95%CI: 8.532, 26.720) reflecting the high burden of the problem in the advanced courses of HIV/AIDS treatment and care. Conclusions The proportion of undernutrition among SLART users in Northern Ethiopia is high. During HIV therapy, a client’s overall nutritional health is predicted by their prior undernutrition condition. This highlights the need for comprehensive nutritional assessment, counseling, and monitoring of the nutritional status of SLART users in the area with emphasis on an early identification of possible barriers to the improvement of such conditions. Promoting the consumption of nutrient-dense local foods and appropriate food preparation methods in addition to nutritional support are vital in this setting.https://doi.org/10.1186/s12889-024-21274-2AdultAntiretroviralEthiopiaSecondlineTreatmentUndernutrition |
| spellingShingle | Seteamlak Adane Masresha Atitegeb Abera Kidie Getahun Fentaw Mulaw Fentaw Wassie Feleke Mesfin Wudu Kassaw Tadesse Mamo Dejene Aychew Kassie Gidafie Fassikaw Kebede Bizuneh Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia BMC Public Health Adult Antiretroviral Ethiopia Secondline Treatment Undernutrition |
| title | Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia |
| title_full | Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia |
| title_fullStr | Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia |
| title_full_unstemmed | Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia |
| title_short | Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia |
| title_sort | under nutrition and its associated factors among adult second line antiretroviral treatment users in northern ethiopia |
| topic | Adult Antiretroviral Ethiopia Secondline Treatment Undernutrition |
| url | https://doi.org/10.1186/s12889-024-21274-2 |
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