ACAT1/SOAT1 maintains adipogenic ability in preadipocytes by regulating cholesterol homeostasis

ACAT1/SOAT1 maintains adipogenic ability in preadipocytes by regulating cholesterol homeostasis

Maintaining cholesterol homeostasis is critical for preserving adipocyte function during the progression of obesity. Despite this, the regulatory role of cholesterol esterification in governing adipocyte expandability has been understudied. Acyl-coenzyme A (CoA):cholesterol acyltransferase/Sterol O-...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qing Liu, Xiaolin Wu, Wei Duan, Xiaohan Pan, Martin Wabitsch, Ming Lu, Jing Li, Li-Hao Huang, Zhangsen Zhou, Yuyan Zhu
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	Journal of Lipid Research
Subjects:	adipocytes cholesterol/metabolism cholesterol/trafficking lipid rafts nuclear receptors/SREBP PPARγ
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227524001858
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The role of cholesterol in modifying the lipid-lowering effects of Fuzhuan brick-tea in Caenorhabditis elegans via SBP-1/SREBP
by: Lianyun Pan, et al.
Published: (2023-11-01)

Regulation of cholesterol biosynthesis by CTCF and H3K27 methylation is critical for cell migration
by: Lukasz Stanislaw Kaczmarczyk, et al.
Published: (2024-12-01)

HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content
by: Dedipya Yelamanchili, et al.
Published: (2025-01-01)

Acetyl-L-carnitine ameliorates atherosclerosis in LDLR−/− mice by modulating cholesterol metabolism through SREBP2-dependent cholesterol biosynthesis
by: Jingci Xing, et al.
Published: (2024-12-01)

TMAO is involved in sleep deprivation-induced cognitive dysfunction through regulating astrocytic cholesterol metabolism via SREBP2
by: Shan Zhu, et al.
Published: (2024-11-01)

Cholesterol metabolism regulator SREBP2 inhibits HBV replication via suppression of HBx nuclear translocation
by: Fan Yang, et al.
Published: (2025-01-01)

Bacillus lipopeptides inhibit lipase activity and promote 3T3-L1 preadipocyte differentiation
by: Meichun Chen, et al.
Published: (2024-12-01)

Free Cholesterol‐Induced Liver Injury in Non‐Alcoholic Fatty Liver Disease: Mechanisms and a Therapeutic Intervention Using Dihydrotanshinone I
by: Jia‐Wen Shou, et al.
Published: (2025-01-01)

Reconstruction and computer analysis of the structural and functional organization of the gene network regulating cholesterol biosynthesis in humans and the evolutionary characteristics of the genes involved in the network
by: A. D. Mikhailova, et al.
Published: (2025-01-01)

Association between residual cholesterol and sarcopenia in American adults
by: Jianzhao Li, et al.
Published: (2024-11-01)

Effect of the Synthesit Dietary Supplement on Serum Cholesterol Levels
by: Patrik Kusnir, et al.
Published: (2024-11-01)

Development and characterization of fluorescent cholesteryl probes with enhanced solvatochromic and pH-sensitive properties for live-cell imaging
by: Vicente Rubio, et al.
Published: (2024-12-01)

Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization
by: Syed A. H. Zaidi, et al.
Published: (2025-01-01)

Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice
by: Tong Zhao, et al.
Published: (2025-01-01)

Role of high-density lipoprotein cholesterol in health and diseases
by: Brijesh Yadav, et al.
Published: (2021-01-01)

Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3
by: Zeina Salloum, et al.
Published: (2024-04-01)

In Vitro Cholesterol Uptake by the Microflora of Selected Kefir Starter Cultures
by: Małgorzata Ziarno, et al.
Published: (2024-11-01)

The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
by: Deniz Uluışık, et al.

Associations of Adipokine Levels With Levels of Remnant Cholesterol: The Multi‐Ethnic Study of Atherosclerosis
by: Renato Quispe, et al.
Published: (2024-09-01)

Association between calculated remnant cholesterol levels and incident risks of Alzheimer’s disease among elderly patients with type 2 diabetes: a real-world study
by: Huimeng Jia, et al.
Published: (2024-11-01)

Serum cholesterol in children with ASD
by: Firas Fadhil Alyaseen
Published: (2024-09-01)

GC-MS analysis of cholesterol lowering dietary supplements
by: Velislava Todorova, et al.
Published: (2024-12-01)

Longitudinal changes in remnant cholesterol and the risk of cardiovascular disease
by: Yijun Zhang, et al.
Published: (2025-01-01)

Real-world data lipid profiles in one million colombian adults: The LiPAC million person study
by: Claudia C. Colmenares-Mejía, et al.
Published: (2024-12-01)

Association of cumulative non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with the risk of cardiometabolic disease
by: Luqing Liu, et al.
Published: (2024-11-01)

Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children
by: Ana Torres-Costoso, et al.
Published: (2025-01-01)

Carotenoid Interactions with PCSK9: Exploring Novel Cholesterol-Lowering Strategies
by: Alessandro Medoro, et al.
Published: (2024-11-01)

Discordance Between Triglycerides, Remnant Cholesterol and Systemic Inflammation in Patients with Schizophrenia
by: Jeffrey Wang, et al.
Published: (2024-12-01)

Health interest of cholesterol and phytosterols and their contribution to one health approach: Review
by: Souleymane Zio, et al.
Published: (2024-11-01)

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD
by: Shaowei Wang, et al.
Published: (2025-02-01)

The relationship between cholesterol levels and thyroid eye disease
by: Caroline Cardo, et al.
Published: (2025-02-01)

Cardio-Protective-Promoting Properties of Functional Foods Inducing HDL-Cholesterol Levels and Functionality
by: Athina Velissaridou, et al.
Published: (2024-09-01)

Synchronization of oestrus in different sheep breeds by progesterone+ecg and investigation of cholesterol and progesterone levels
by: Mehmet Uçar, et al.

An equation for calculating small dense low-density lipoprotein cholesterol
by: Tianjiao Han, et al.
Published: (2024-11-01)

Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
by: L. A. Yakovishin, et al.
Published: (2020-12-01)

Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition
by: Shuangqian Yan, et al.
Published: (2025-01-01)

Association between platelet-to-high-density lipoprotein cholesterol ratio and future stroke risk: a national cohort study based on CHARLS
by: Xin Hou, et al.
Published: (2024-11-01)

Article RETRACTED due to manipulation by the authors The BMI, fat percentage and total cholesterol of athletes: what is their status?
by: Isti Dwi Puspita Wati, et al.
Published: (2024-01-01)

The levels of the blood serum thyroid hormones, glucose and cholesterol in swiss brown cows which were at the lactation
by: Tufan Keçeci, et al.

Recent advances in the anti-tumor activities of saponins through cholesterol regulation
by: Min Jiang, et al.
Published: (2025-01-01)