Candida (Candidozyma) Auris: From Colonization to Invasive Disease

Currently, Candida auris (C. auris) (infections in healthcare settings have become increasingly concerning due to their antifungal resistance and the difficulties associated with preventing cross-contamination. Since 2021, C. auris cases and outbreaks have been reported in several provinces across o...

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Bibliographic Details
Main Authors: Burcu AÇIKALIN ARIKAN, Nurbanu SEZAK
Format: Article
Language:English
Published: Galenos Yayinevi 2025-08-01
Series:Forbes Tıp Dergisi
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Online Access:https://forbestip.org/articles/candida-candidozyma-auris-from-colonization-to-invasive-disease/doi/forbes.galenos.2025.00378
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Summary:Currently, Candida auris (C. auris) (infections in healthcare settings have become increasingly concerning due to their antifungal resistance and the difficulties associated with preventing cross-contamination. Since 2021, C. auris cases and outbreaks have been reported in several provinces across our country. This rapidly spreading Candida species represents a healthcare-associated infection that is particularly challenging to control due to its resistance profile. It easily colonizes and causes infections in patients with prolonged antibiotic use, those with indwelling devices such as central and peripheral vascular catheters that facilitate colonization and adherence, elderly individuals, surgical patients, and immunosuppressed individuals. Studies have shown that colonization can persist for months or even years. C. auris may lead to a variety of infections, including bloodstream infections, myocarditis, surgical site infections, burn wound infections, catheter site abscesses, otitis, meningitis, and bone and joint infections. Whenever possible, infected or colonized patients should be cared for in single-occupancy rooms, and education on hand hygiene and isolation precautions should be provided to patients, their families, and healthcare workers.
ISSN:2757-5241