Targeting Toll-Like Receptors for Treatment of SLE
Toll-like receptors (TLRs) are important innate immune receptors for the identification and clearance of invading pathogens. Twelve TLRs that recognize various conserved components of microorganisms are currently known. Among these, the endosomal TLRs 3, 7/8, and 9 recognize dsRNA, ssRNA, and CpG...
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Main Authors: | Christopher G. Horton, Zi-jian Pan, A. Darise Farris |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2010/498980 |
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