Joint ancestry and association testing in admixed individuals.

For samples of admixed individuals, it is possible to test for both ancestry effects via admixture mapping and genotype effects via association mapping. Here, we describe a joint test called BMIX that combines admixture and association statistics at single markers. We first perform high-density admi...

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Bibliographic Details
Main Authors: Daniel Shriner, Adebowale Adeyemo, Charles N Rotimi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002325&type=printable
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