Dual regulation of gastrointestinal tumor progression by the IFN-γ/STAT1 pathway and prospects for targeted therapy

Dual regulation of gastrointestinal tumor progression by the IFN-γ/STAT1 pathway and prospects for targeted therapy

Gastrointestinal malignant tumors exhibit a high incidence and mortality rate among all malignancies worldwide, making them a significant concern within the field of oncology. Targeted therapy for gastrointestinal tumors has become a hot topic in recent years, and its specific mechanism remains to b...

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Bibliographic Details
Main Authors: Yuhao Liu, Yuxin Huang, Qiaoying He, Yuyan Shen, Yaoling Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
gastrointestinal tumors
the IFN-γ/STAT1 pathway
immunity
inflammation
tumor cell proliferation and metastasis
tumor cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1598170/full
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