Molecular testing stratifies the risk of structural recurrence in high risk differentiated thyroid cancer: a retrospective cohort study

Molecular testing stratifies the risk of structural recurrence in high risk differentiated thyroid cancer: a retrospective cohort study

BackgroundHigh-risk differentiated thyroid cancer in 2015 American Thyroid Association risk stratification system (ATA-RSS) exhibits a significantly increased probability of recurrence and poor outcomes. This study aimed to investigate the molecular profiles of high-risk differentiated thyroid cance...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jie Liu, Wensi Gao, Xiong Zheng, Shuping Wu, Yi Shi, Feng Wang, Yu Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Endocrinology
Subjects:	thyroid cancer risk stratification molecular testing recurrence molecular profile
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1508404/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Clinicopathological and molecular characteristics of papillary thyroid carcinoma in adolescent and young adult patients
by: Van Phu Thang Nguyen, et al.
Published: (2025-02-01)

A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer☆
by: S. Hussung, et al.
Published: (2025-03-01)

MRI as an assessment tool for prognostic risk stratification of endometrial carcinoma patients based on molecular classification
by: Tingting Cui, et al.
Published: (2024-12-01)

Lobectomy sufficiency for 1–4 cm differential thyroid cancer: a large retrospective study in China
by: Jun Xu, et al.
Published: (2024-12-01)

Cost-effectiveness analysis of molecular testing for cytologically indeterminate thyroid nodules
by: Navjit Dharampal, et al.
Published: (2022-12-01)

Salvage radiofrequency ablation followed by external beam radiotherapy for inoperable recurrent differentiated thyroid cancer
by: Chung-Shih Chen, et al.
Published: (2024-12-01)

Occurrence and management of thrombosis recurrence and bleeding in low-molecular-weight heparin-treated patients with cancer-associated thrombosis: a French nationwide cohort study
by: Isabelle Mahé, et al.
Published: (2025-01-01)

Attempts to identify the molecular cause of autoinflammatory recurrent fever
by: Oksana Boyarchuk, et al.
Published: (2024-11-01)

Patterns of regional recurrence in papillary thyroid cancer patients with lateral neck metastases undergoing neck dissection
by: Jason J. Xu, et al.
Published: (2017-05-01)

Ultrasound-guided microwave ablation versus surgery for low-risk solitary papillary thyroid microcarcinoma: a propensity-matched cohort study
by: Yujie Ren, et al.
Published: (2025-01-01)

Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: a retrospective cohort study
by: Usman Khan, et al.
Published: (2020-11-01)

Gross recurrent laryngeal nerve invasion by extranodal extension in thyroid carcinoma
by: Xin Li, et al.
Published: (2025-01-01)

EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles
by: Noha Elsherbini, et al.
Published: (2022-11-01)

Understanding HLA-DQ in renal transplantation: a mini-review
by: Rajdeep Das, et al.
Published: (2025-02-01)

Novel perspectives on the pharmacological treatment of thyroid-associated ophthalmopathy
by: Zilin Li
Published: (2025-01-01)

Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study
by: Takahiro Inaishi, et al.
Published: (2024-12-01)

Investigation of Scutellaria Barbata’s immunological mechanism against thyroid cancer using network pharmacology and experimental validation
by: Gen Ouyang, et al.
Published: (2025-01-01)

Computational and experimental exploration of morpholine pendent 2-hydrazineyl thiazole: Insights from DFT, ADME profiling, antifungal efficacy and molecular docking analyses
by: Vishnu A. Adole, et al.
Published: (2025-01-01)

Paradigms of intraoperative neuromonitoring in paediatric thyroid surgery
by: Yuchuan Li, et al.
Published: (2025-01-01)

Thyroid nodule rupture after thermal ablation for benign thyroid nodules: incidence, risk factors, and clinical management
by: Yu-tong Liu, et al.
Published: (2025-12-01)

Leveraging computational approaches in identifying novel HER-2 + breast cancer potential therapeutics: integrating virtual screening and molecular dynamics simulation
by: Olawale Quadri Bolaji, et al.
Published: (2025-01-01)

The Performance of the American Thyroid Association (ATA) and American College of Radiology (ACR-TIRAD) Thyroid Nodule Risk-Stratification Systems in Determining High-Risk Nodules, and the Correlation of Site, Size, and Autoimmunity with High-Risk Features
by: Ibrahim H. Hussein, et al.
Published: (2024-12-01)

Molecular modelling of four penicillins: bencylpenicillin, phenoxymethylpenicillin, ampicillin and amoxicillin
by: Elso Manuel Cruz Cruz, et al.
Published: (2009-09-01)

Comprehensive analysis of clinicopathologic and prognostic features in locally advanced thyroid papillary cancer
by: Liang Jiwang, et al.
Published: (2025-03-01)

Analysis of the prognostic value of thyroglobulin antibody change trends during follow-up after 131I treatment in patients with differentiated thyroid carcinoma
by: Hua Ge, et al.
Published: (2025-02-01)

The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study
by: Mark Sasson, et al.
Published: (2017-04-01)

Molecular network analysis for detecting HIV transmission clusters: insights and implications
by: Yangyang Liu, et al.
Published: (2025-01-01)

A Study of Molecular Subtypes (Profile) of Colorectal Cancer and Their Correlation with Clinical and Pathological Profile in a Tertiary Care Center in India
by: Srujana Joga, et al.

An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma
by: Michele Massimino, et al.
Published: (2025-01-01)

Elucidating the Mechanism of Action of Umami-Enhancing Peptides Derived from Chicken Based on Molecular Simulation
by: ZHANG Jingcheng, HE Wei, LIANG Li, ZHANG Yuyu
Published: (2024-12-01)

Bridging Molecular Docking to Molecular Dynamics to Enlighten Recognition Processes of Tailored D-A/D-A-D Types' AIEgens with HSA/BSA
by: Harun Nalçakan, et al.
Published: (2023-09-01)

Risk factors of thyroid dysfunction in patients with rheumatoid arthritis
by: Lan Li, et al.
Published: (2024-06-01)

Molecular Generation and Optimization of Molecular Properties Using a Transformer Model
by: Zhongyin Xu, et al.
Published: (2024-03-01)

First-trimester Doppler Ultrasound for Predicting Successful Management of Pregnancy with Recurrent Pregnancy Losses Due to Antiphospholipid Syndrome and Thrombophilia: A Cohort Study
by: Muhammad Adrianes Bachnas, et al.
Published: (2024-12-01)

Pattern of Thyroid Disorders in a Tertiary Care Centre of a High-Altitude Region of Nepal: A hospital-based retrospective study
by: Tirtha Narayan Sah, et al.
Published: (2024-12-01)

Pattern of Thyroid Disorders in a Tertiary Care Centre of a High-Altitude Region of Nepal: A hospital-based retrospective study
by: Tirtha Narayan Sah, et al.
Published: (2024-12-01)

Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years
by: Ambili Susan Jacob, et al.
Published: (2025-01-01)

Fundamentals of Molecular Spectroscopy /
by: Banwell, C. N.
Published: (1994)

Development and validation of a recurrence risk prediction model for elderly schizophrenia patients
by: Biqi Zu, et al.
Published: (2025-01-01)

The Electron Microscope in Molecular Biology /
by: Haggis ,G.H
Published: (1968)