Mitochondrial DNA copy number and the risk of autoimmune diseases: A Mendelian randomization study with meta-analysis

Mitochondrial DNA copy number and the risk of autoimmune diseases: A Mendelian randomization study with meta-analysis

Background: Mitochondrial DNA plays a crucial role in the pathophysiology of autoimmune diseases (ADs). However, the association between mitochondrial DNA copy number (mtDNA-CN) and ADs risk is controversial. In this study, Mendelian randomization (MR) analysis and meta-analysis were performed using...

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Bibliographic Details
Main Authors: Mingzhu Liu, Xiongquan Long, Shuangshuang Fu, Yuyang Zhang, Zihao Liu, Xiaoping Xu, Minghao Wu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Translational Autoimmunity
Subjects:
Mitochondrial DNA copy number
Autoimmune diseases
Mendelian randomization
Genetic level
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909024000212
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