Phospho-relay feedback loops control egress vs. intracellular development in Toxoplasma gondii
Summary: The intracellular parasite Toxoplasma gondii alternates between a motile invasive and a quiescent intracellular replicative form, yet how these transitions are regulated is unknown. A positive feedback loop involving protein kinase G (PKG) and calcium-dependent PKs (CDPKs) controls motility...
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Main Authors: | Ja E. Claywell, Yong Fu, L. David Sibley |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725000312 |
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