Single-cell RNA sequencing technology was employed to construct a risk prediction model for genes associated with pyroptosis and ferroptosis in lung adenocarcinoma

Single-cell RNA sequencing technology was employed to construct a risk prediction model for genes associated with pyroptosis and ferroptosis in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD) is one of the most common subtypes of non-small cell lung cancer, and its mortality rate remains high. As a programmed cell death mode closely related to inflammation, pyroptosis has been found to play an important regulatory role in the tumor immune mi...

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Bibliographic Details
Main Authors: Longfei Ji, Binyu Wang, Danfei Shi, Weiyun Shen, Xinmin Li, Yong Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Respiratory Research
Subjects:
Lung adenocarcinoma
Pyroptosis
Single-cell RNA sequencing
Ferroptosis
Prognostic model
Tumor immune microenvironment
Online Access:https://doi.org/10.1186/s12931-025-03323-5
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