Alcohol intake exacerbates experimental autoimmune prostatitis through activating PI3K/AKT/mTOR pathway-mediated Th1 differentiation

Alcohol intake exacerbates experimental autoimmune prostatitis through activating PI3K/AKT/mTOR pathway-mediated Th1 differentiation

BackgroundEpidemiological investigations have revealed a significant association between alcohol consumption and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Nevertheless, the potential mechanisms are still inadequately revealed. This research aimed to investigate the impact of alcoho...

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Bibliographic Details
Main Authors: Shun Xu, Jing Chen, Shaoyu Yue, Yifan Zhang, Shengyu Zhao, Yongtao Hu, Cheng Zhang, Wenrui Guan, Li Zhang, Ligang Zhang, Chaozhao Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
alcohol
CP/CPPS
PI3K/AKT/mTOR pathway
Th1 cell
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1512456/full
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