Understanding Powder Behavior in Continuous Feeding: Powder Densification and Screw Layering

Understanding Powder Behavior in Continuous Feeding: Powder Densification and Screw Layering

Background: Precise continuous feeding of active pharmaceutical ingredients (APIs) and excipients is crucial in a continuous powder-to-tablet manufacturing setup, as any inconsistency can affect the final tablet quality. Method: This study investigated the impact of various materials on the performa...

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Bibliographic Details
Main Authors: Sara Fathollahi, Pauline H. M. Janssen, Bram Bekaert, Dirk Vanderroost, Valerie Vanhoorne, Bastiaan H. J. Dickhoff
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Powders
Subjects:
continuous feeding
loss-in-weight (LIW) feeder
screw layering
densification
feed factor variation
API
Online Access:https://www.mdpi.com/2674-0516/3/4/26
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