Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review
Abstract Combined small-cell lung carcinoma (C-SCLC) is an uncommon lung cancer variant characterized by the presence of multiple pathological types within a single case or tumor, typically associated with poor outcomes. The high rate of misdiagnosis and low rate of accurate diagnosis for C-SCLC ste...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
|
| Series: | Journal of Cancer Research and Clinical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00432-025-06283-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849238099385647104 |
|---|---|
| author | Xiao Wu Ke Fang Wenya Huang Gang Chen Dingkun Wang |
| author_facet | Xiao Wu Ke Fang Wenya Huang Gang Chen Dingkun Wang |
| author_sort | Xiao Wu |
| collection | DOAJ |
| description | Abstract Combined small-cell lung carcinoma (C-SCLC) is an uncommon lung cancer variant characterized by the presence of multiple pathological types within a single case or tumor, typically associated with poor outcomes. The high rate of misdiagnosis and low rate of accurate diagnosis for C-SCLC stem from limitations in sample collection, which primarily involves bronchoscopy and aspiration biopsy instead of surgical resection or autopsy. Moreover, standard chemotherapy for patients with C-SCLC has not yet been established. Cases of combined small-cell lung cancer with adenocarcinoma are extremely rare. Herein, we report a case of the detailed whole-process treatment of combined small-cell lung cancer with adenocarcinoma and review the literature. |
| format | Article |
| id | doaj-art-87caa89f70324c9a938baf68cadcc045 |
| institution | Kabale University |
| issn | 1432-1335 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Cancer Research and Clinical Oncology |
| spelling | doaj-art-87caa89f70324c9a938baf68cadcc0452025-08-20T04:01:46ZengSpringerJournal of Cancer Research and Clinical Oncology1432-13352025-08-0115181710.1007/s00432-025-06283-xCombined small-cell lung cancer with adenocarcinoma: a rare case and literatures reviewXiao Wu0Ke Fang1Wenya Huang2Gang Chen3Dingkun Wang4Department of Integrated Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyAbstract Combined small-cell lung carcinoma (C-SCLC) is an uncommon lung cancer variant characterized by the presence of multiple pathological types within a single case or tumor, typically associated with poor outcomes. The high rate of misdiagnosis and low rate of accurate diagnosis for C-SCLC stem from limitations in sample collection, which primarily involves bronchoscopy and aspiration biopsy instead of surgical resection or autopsy. Moreover, standard chemotherapy for patients with C-SCLC has not yet been established. Cases of combined small-cell lung cancer with adenocarcinoma are extremely rare. Herein, we report a case of the detailed whole-process treatment of combined small-cell lung cancer with adenocarcinoma and review the literature.https://doi.org/10.1007/s00432-025-06283-xCombined small-cell lung carcinomaSmall cell lung cancerImmunotherapyRadiotherapyCase report |
| spellingShingle | Xiao Wu Ke Fang Wenya Huang Gang Chen Dingkun Wang Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review Journal of Cancer Research and Clinical Oncology Combined small-cell lung carcinoma Small cell lung cancer Immunotherapy Radiotherapy Case report |
| title | Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review |
| title_full | Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review |
| title_fullStr | Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review |
| title_full_unstemmed | Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review |
| title_short | Combined small-cell lung cancer with adenocarcinoma: a rare case and literatures review |
| title_sort | combined small cell lung cancer with adenocarcinoma a rare case and literatures review |
| topic | Combined small-cell lung carcinoma Small cell lung cancer Immunotherapy Radiotherapy Case report |
| url | https://doi.org/10.1007/s00432-025-06283-x |
| work_keys_str_mv | AT xiaowu combinedsmallcelllungcancerwithadenocarcinomaararecaseandliteraturesreview AT kefang combinedsmallcelllungcancerwithadenocarcinomaararecaseandliteraturesreview AT wenyahuang combinedsmallcelllungcancerwithadenocarcinomaararecaseandliteraturesreview AT gangchen combinedsmallcelllungcancerwithadenocarcinomaararecaseandliteraturesreview AT dingkunwang combinedsmallcelllungcancerwithadenocarcinomaararecaseandliteraturesreview |