Risk of Infective Endocarditis Following Invasive Dental Procedures: A Systematic Review and Meta-Analysis
ObjectivesThis systematic review and meta-analysis aimed to synthesize evidence and determine the association between IE and dental procedures, including invasive and non-invasive procedures.MethodsWe conducted a systematic search of PubMed, Google Scholar, and Cochrane databases for studies involvi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
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| Series: | Public Health Reviews |
| Subjects: | |
| Online Access: | https://www.ssph-journal.org/articles/10.3389/phrs.2024.1607684/full |
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| Summary: | ObjectivesThis systematic review and meta-analysis aimed to synthesize evidence and determine the association between IE and dental procedures, including invasive and non-invasive procedures.MethodsWe conducted a systematic search of PubMed, Google Scholar, and Cochrane databases for studies involving procedures such as tooth extraction, scaling, endodontic treatment, oral surgery, and periodontal treatment involving individuals aged ≥15 years. The primary outcome was the incidence of IE following these procedures.ResultsAn association was found between IE and invasive dental procedures (OR 1.49, 95% CI 1.25–1.76; p < 0.00001). Subgroup analysis showed an increased risk of IE following tooth extraction (OR 2.73, 95% CI 1.46–5.11; p = 0.002) and oral surgery (OR 6.33, 95% CI 2.43–16.49; p = 0.0002) in high-risk patients.ConclusionOur study found a strong association between invasive dental procedures and increased IE risk, particularly for tooth extraction and oral surgery in high-risk individuals.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023488546, Identifier CRD42023488546. |
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| ISSN: | 2107-6952 |