Aging promotes an increase in mitochondrial fragmentation in astrocytes

Aging promotes an increase in mitochondrial fragmentation in astrocytes

IntroductionBrain aging involves a complex interplay of cellular and molecular changes, including metabolic alterations and the accumulation of senescent cells. These changes frequently manifest as dysregulation in glucose metabolism and mitochondrial function, leading to reduced energy production,...

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Main Authors: Ana Paula Bergamo Araujo, Gabriele Vargas, Lívia de Sá Hayashide, Isadora Matias, Cherley Borba Vieira Andrade, Jorge José de Carvalho, Flávia Carvalho Alcantara Gomes, Luan Pereira Diniz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
brain aging
mitochondrial dysfunction
astrocytes
mitochondrial fragmentation
mitochondrial biogenesis and neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1496163/full
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https://www.frontiersin.org/articles/10.3389/fncel.2024.1496163/full

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