Comprehensive analysis of ferroptosis-related genes reveals potential therapeutic targets in osteoporosis patients: a computational analysis and in vitro experiments

Comprehensive analysis of ferroptosis-related genes reveals potential therapeutic targets in osteoporosis patients: a computational analysis and in vitro experiments

BackgroundFerroptosis-related genes have been reported to play important roles in many diseases, but their molecular mechanisms in osteoporosis have not been elucidated.MethodsBased on two independent GEO datasets (GSE35956 and GSE35958), and GSE35959 as the validation dataset, we comprehensively el...

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Bibliographic Details
Main Authors: Sihui Chen, Yi Jiang, Guoqin Xie, Peng Wu, Jinyu Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Genetics
Subjects:
KMT2D
osteoporosis
ferroptosis
aging
BMSCs
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1522809/full
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