Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies

Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies

ABSTRACT Introduction Gut dysbiosis is closely related to the development of sarcopenic obesity (SO). Melatonin (MLT) regulates gut microbiota and promotes the production of short‐chain fatty acids (SCFAs). However, whether MLT affects SO through the gut microbiota and SCFAs remains unclear. This st...

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Bibliographic Details
Main Authors: Xiaoxing Mo, Lihui Shen, Xinyu Wang, Wenqing Ni, Linyan Li, Lili Xia, Hongjie Liu, Ruijie Cheng, Lin Wen, Jian Xu, Liegang Liu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
gut microbiota
melatonin
oxidative stress
protein synthesis
sarcopenic obesity
short‐chain fatty acids
Online Access:https://doi.org/10.1002/jcsm.13869
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