The adaptor protein Miro1 modulates horizontal transfer of mitochondria in mouse melanoma models

The adaptor protein Miro1 modulates horizontal transfer of mitochondria in mouse melanoma models

Summary: Recent research has shown that mtDNA-deficient cancer cells (ρ0 cells) acquire mitochondria from tumor stromal cells to restore respiration, facilitating tumor formation. We investigated the role of Miro1, an adaptor protein involved in movement of mitochondria along microtubules, in this p...

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Main Authors: Jaromir Novak, Zuzana Nahacka, Gabriela L. Oliveira, Petra Brisudova, Maria Dubisova, Sarka Dvorakova, Sona Miklovicova, Marketa Dalecka, Verena Puttrich, Lenka Grycova, Silvia Magalhaes-Novais, Catarina Mendes Correia, Jennifer Levoux, Ludek Stepanek, Jan Prochazka, David Svec, David Pajuelo Reguera, Guillermo Lopez-Domenech, Renata Zobalova, Radek Sedlacek, Mikkel G. Terp, Payam A. Gammage, Zdenek Lansky, Josef Kittler, Paulo J. Oliveira, Henrik J. Ditzel, Michael V. Berridge, Anne-Marie Rodriguez, Stepana Boukalova, Jakub Rohlena, Jiri Neuzil
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015055
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