Wharton’s Jelly Bioscaffolds Improve Cardiac Repair with Bone Marrow Mononuclear Stem Cells in Rats

Wharton’s Jelly Bioscaffolds Improve Cardiac Repair with Bone Marrow Mononuclear Stem Cells in Rats

This study assessed the impact of implanting mononuclear stem cells and Wharton’s Jelly (WJ), either separately or together, on left ventricular dysfunction following myocardial infarction in Wistar rats. Functional and histopathological parameters were analyzed, and a rat model of left anterior des...

Full description

Saved in:

Bibliographic Details
Main Authors:	Luize Kremer Gamba, Laiza Kremer Gamba, Camila da Costa, Aline Luri Takejima, Rossana Baggio Simeoni, Isabella Cristina Mendes Rossa, Anna Clara Faidiga Silva, Julia Letícia de Bortolo, Marcos Antônio Denk, Seigo Nagashima, Carlos de Almeida Barbosa, Paulo Cesar Lock Silveira, Júlio César Francisco, Luiz César Guarita-Souza
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Series:	Journal of Functional Biomaterials
Subjects:	Wharton’s Jelly bioscaffolds cardiac repair bone marrow mononuclear stem cells myocardial infarction tissue engineering
Online Access:	https://www.mdpi.com/2079-4983/16/5/175
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Rapid isolation and characterization of Wharton's jelly-derived mesenchymal stem cells maintained in fresh-prepared human AB-serum
by: Yudy Tjahjono, et al.
Published: (2025-04-01)

Enhancing adipogenesis in Wharton’s jelly multipotent mesenchymal stromal cells through lipidomic insights and fatty acid supplementation
by: Olena Rogulska, et al.
Published: (2025-08-01)

A Review Study on the Fabrication and Use of Bioscaffolds and Biologically Simulated Bone Materials in Bone Regeneration
by: amirreza hajati Ziabari, et al.
Published: (2025-03-01)

Pooling umbilical cord-mesenchymal stromal cells derived from selected multiple donors reduces donor-dependent variability and improves their immunomodulatory properties
by: Miryam Mebarki, et al.
Published: (2025-05-01)

The Vertebral Bone Marrow clot as cell therapy and multifunctional bioscaffold for spinal fusion surgery: protocol for a randomized clinical trial
by: Maria Sartori, et al.
Published: (2025-05-01)

Protective Effect of Aerobic Training and Royal Jelly on Cellular senescence Markers of Cardiomyocytes in Obese Rats
by: Iraj Hoseinzade, et al.
Published: (2022-06-01)

BIOLOGICAL ACTIVITY OF THE COMPONENTS OF ROYAL JELLY AND BEE VENOM
by: S. G. Mardanly, et al.
Published: (2018-11-01)

Possible effects of royal jelly against neuronal injury in the hippocampus of ovariectomized rats with pentylenetetrazol-induced seizures: Role of luteinizing and follicle-stimulating hormones
by: Asma Momeni, et al.
Published: (2025-03-01)

Inhibitory Effect of Ejiao Jelly Extract on Hyaluronidase Activity and Its Influence on Lipid Synthesis in SZ95 Cells
by: MENG Ling-feng, et al.
Published: (2025-07-01)

Quantitative detection of major royal jelly proteins 1-3 by ultra-high performance liquid chromatography-tandem mass spectrometry
by: CHEN Yong, et al.
Published: (2022-12-01)

Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice
by: Hojat Anbara, et al.
Published: (2024-12-01)

Xylitol substitution in the development of reduced-sugar gummy jelly mixed with Gymnema inodorum (Lour.) Decne leaf powder
by: Tem Sasiluksananukul, et al.
Published: (2025-06-01)

Development of the formulation and technology for functional jelly using mulberry syrup
by: A. I. Blyagoz, et al.
Published: (2022-04-01)

Combination of Jelly Bump and Protein Deposits in a Conventional Prosthetic Contact Lens: A Rare Case Report
by: Suraj Kumar Chaurasiya, et al.
Published: (2025-01-01)

Behind the Therapeutic Effects of Royal Jelly: Recent Advances in the Specific Properties of 10-Hydroxydecanoic Acid
by: Carla Gasbarri, et al.
Published: (2025-06-01)

Embryo development in Mexican axolotl (Ambystoma mexicanum): a stage morphological study
by: Fernando García-González, et al.
Published: (2025-04-01)

THE INCREASED SAFETY JELLY DISHES FOR SCHOOL FEEDING
by: Galina Valentinovna Ivanova, et al.
Published: (2022-10-01)

Comparison between wharton’s jelly and collagen natural hydrogels for human ovarian follicle transplantation as an artificial ovary
by: Farnaz Tajbakhsh, et al.
Published: (2025-01-01)

Research of tribotechnical characteristics of materials used in the development of compositions of lubricants for casting under pressure of aluminum alloys and polymeric products
by: A. M. Mikhaltsov, et al.
Published: (2020-04-01)

Development of a tissue-specific bioscaffold for intestinal stem cell culture.
by: Sachin Kakar, et al.
Published: (2025-01-01)

Xenotransplantation of Human Umbilical Mesenchymal Stromal Cells Derived from Wharton's Jelly Mitigates Mouse Amyotrophic Lateral Sclerosis
by: Chun-Fu Lin, et al.
Published: (2025-07-01)

Synergistic Improvement in Children with Cerebral Palsy Who Underwent Double-Course Human Wharton’s Jelly Stem Cell Transplantation
by: Xiaojun Fu, et al.
Published: (2019-01-01)

In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans
by: A. S. Ponomareva, et al.
Published: (2022-12-01)

Tendon Tissue Repair in Prospective of Drug Delivery, Regenerative Medicines, and Innovative Bioscaffolds
by: Muhammad Nadeem Hafeez, et al.
Published: (2021-01-01)

Effects of Serial Passage on the Characteristics and Cardiac and Neural Differentiation of Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells
by: Jianchun Lian, et al.
Published: (2016-01-01)

La notte di Milano: problemi e opportunità in una fase di rigenerazione urbana
by: Simone Gamba
Published: (2019-07-01)

Systems Development for Records Archiving and Digital Documents Repository: A Case Study
by: Michael P. Gamba, et al.
Published: (2014-07-01)

Evaluating Wharton’s Jelly-Derived Mesenchymal Stem Cell’s Survival, Migration, and Expression of Wound Repair Markers under Conditions of Ischemia-Like Stress
by: Iris Himal, et al.
Published: (2017-01-01)

Comparative Evaluation of Human Mesenchymal Stem Cells of Fetal (Wharton's Jelly) and Adult (Adipose Tissue) Origin during Prolonged In Vitro Expansion: Considerations for Cytotherapy
by: I. Christodoulou, et al.
Published: (2013-01-01)

Optimization of hydroxyapatite-PEGDA slurry for vat polymerization: Microstructure and mechanical properties of 3D printed bioscaffolds
by: Liana Mkhitaryan, et al.
Published: (2025-09-01)

Metaquímicas del litio
by: Martina Gamba, et al.
Published: (2025-08-01)

Wharton’s Duct Sialolith of Unusual Size: A Case Report with a Review of the Literature
by: Nithin Mathew Cherian, et al.
Published: (2014-01-01)

SSC Graduate Students' Difficulties in Doing Research
by: Magdalena M. Ocbian, et al.
Published: (2015-06-01)

A democracia em questão: com a fala, as mulheres militantes de esquerda durante a ditadura militar nos anos de 1964 a 1985
by: Torres, Mateus Gamba, et al.
Published: (2019-01-01)

Thomas Dutoit. A Rose, A Ghost, in Edith Wharton. Reading Proserpinean Poetics in The Custom of the Country.
by: Cornelius Crowley
Published: (2006-03-01)

Conditioned Medium of IGF1-Induced Human Wharton’s Jelly Mesenchymal Stem Cells Effects on Sox9 Gene Expression and Level of COL2 and IL1β in Osteoarthritic Chondrocytes
by: Wahyu Widowati, et al.
Published: (2024-12-01)

Assessment of Lithuanian Energy Sector Influence on GDP
by: Irena Mačerinskienė, et al.
Published: (2017-12-01)

Financial Sustainability of Sorsogon State University: An Assessment
by: Maryjean Niemo–Gamba, et al.
Published: (2022-10-01)

Atención en salud a las mujeres víctimas de violencia sexual en un municipio de Colombia
by: Damaris Barragán Gamba, et al.
Published: (2021-10-01)

Atención en salud a las mujeres víctimas de violencia sexual en un municipio de Colombia
by: Damaris Barragán Gamba, et al.
Published: (2021-10-01)