Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed
Pesticides and their transformation products are found in raw agricultural and processed food products, posing risks to human health. Therefore, a thorough investigation of dimethachlon’s dissipation, metabolites, residue levels in crops, and changes during food processing is essential for an accura...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
|
| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535224004325 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846164554966368256 |
|---|---|
| author | Lianhong Mou Ling Wu Ling Liu Yu Xiang Deyu Hu Yuping Zhang |
| author_facet | Lianhong Mou Ling Wu Ling Liu Yu Xiang Deyu Hu Yuping Zhang |
| author_sort | Lianhong Mou |
| collection | DOAJ |
| description | Pesticides and their transformation products are found in raw agricultural and processed food products, posing risks to human health. Therefore, a thorough investigation of dimethachlon’s dissipation, metabolites, residue levels in crops, and changes during food processing is essential for an accurate dietary risk assessment. This study identified two metabolites, 4-(3,5-dichloroanilino)-4- oxobutanoic acid (DCBAA) and 3,5-dichloroaniline (3,5-DCA), formed from dimethachlon in crops under field conditions. A precise and sensitive analytical method was developed to detect dimethachlon, DCBAA, and 3,5-DCA in rapeseed pods, seeds, and oil. The half-lives of dimethachlon in rapeseed pods at two sites ranged from 1.61 to 1.67 days. During degradation, the maximum residue levels of DCBAA and 3,5-DCA in rapeseed pods reached 38.59 % and 3.47 % of the initial parent compound concentration, respectively. At harvest (day 10), final dimethachlon residues in rapeseed were 0.11 mg/kg and 0.27 mg/kg. Processing rapeseed into oil through sun-drying and stir-frying reduced dimethachlon residues, with processing factors (PF) of 0.69 and 0.64, respectively. However, pressing the seeds concentrated dimethachlon in the oil, with a PF of 1.92. Notably, DCBAA tended to concentrate during sun-drying but decreased during stir-frying and pressing. Supervised trials indicated that dimethachlon residues in rapeseed posed no long-term dietary risks. |
| format | Article |
| id | doaj-art-85e0998ffde24b1584cce54928983d6c |
| institution | Kabale University |
| issn | 1878-5352 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj-art-85e0998ffde24b1584cce54928983d6c2024-11-18T04:32:44ZengElsevierArabian Journal of Chemistry1878-53522024-12-011712106030Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseedLianhong Mou0Ling Wu1Ling Liu2Yu Xiang3Deyu Hu4Yuping Zhang5State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaCorresponding author.; State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, ChinaPesticides and their transformation products are found in raw agricultural and processed food products, posing risks to human health. Therefore, a thorough investigation of dimethachlon’s dissipation, metabolites, residue levels in crops, and changes during food processing is essential for an accurate dietary risk assessment. This study identified two metabolites, 4-(3,5-dichloroanilino)-4- oxobutanoic acid (DCBAA) and 3,5-dichloroaniline (3,5-DCA), formed from dimethachlon in crops under field conditions. A precise and sensitive analytical method was developed to detect dimethachlon, DCBAA, and 3,5-DCA in rapeseed pods, seeds, and oil. The half-lives of dimethachlon in rapeseed pods at two sites ranged from 1.61 to 1.67 days. During degradation, the maximum residue levels of DCBAA and 3,5-DCA in rapeseed pods reached 38.59 % and 3.47 % of the initial parent compound concentration, respectively. At harvest (day 10), final dimethachlon residues in rapeseed were 0.11 mg/kg and 0.27 mg/kg. Processing rapeseed into oil through sun-drying and stir-frying reduced dimethachlon residues, with processing factors (PF) of 0.69 and 0.64, respectively. However, pressing the seeds concentrated dimethachlon in the oil, with a PF of 1.92. Notably, DCBAA tended to concentrate during sun-drying but decreased during stir-frying and pressing. Supervised trials indicated that dimethachlon residues in rapeseed posed no long-term dietary risks.http://www.sciencedirect.com/science/article/pii/S1878535224004325DimethachlonMetabolitesRapeDegradationProcessing factorsRisk quotient |
| spellingShingle | Lianhong Mou Ling Wu Ling Liu Yu Xiang Deyu Hu Yuping Zhang Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed Arabian Journal of Chemistry Dimethachlon Metabolites Rape Degradation Processing factors Risk quotient |
| title | Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed |
| title_full | Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed |
| title_fullStr | Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed |
| title_full_unstemmed | Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed |
| title_short | Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed |
| title_sort | identification of dimethachlon metabolites and dissipation behavior processing factor and risk assessment of dimethachlon in rapeseed |
| topic | Dimethachlon Metabolites Rape Degradation Processing factors Risk quotient |
| url | http://www.sciencedirect.com/science/article/pii/S1878535224004325 |
| work_keys_str_mv | AT lianhongmou identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed AT lingwu identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed AT lingliu identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed AT yuxiang identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed AT deyuhu identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed AT yupingzhang identificationofdimethachlonmetabolitesanddissipationbehaviorprocessingfactorandriskassessmentofdimethachloninrapeseed |