Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study
ABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) is an established treatment for laterally spreading tumors (LSTs). Hybrid ESD, a novel technique, is gaining popularity for colorectal neoplasms. This study aimed to compare hybrid ESD with conventional ESD for treating LSTs. Method...
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Wiley
2024-12-01
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| Series: | JGH Open |
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| Online Access: | https://doi.org/10.1002/jgh3.70066 |
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| author | Hongxia Li Yiping Hong Linhua Yao Xia Ji Dan Chen Maogen Tao Huihui Yan Jiamin Chen Lingling Wang Liyi Xu Leilei Wang Erfei Luo Jianting Cai Wei Wei |
| author_facet | Hongxia Li Yiping Hong Linhua Yao Xia Ji Dan Chen Maogen Tao Huihui Yan Jiamin Chen Lingling Wang Liyi Xu Leilei Wang Erfei Luo Jianting Cai Wei Wei |
| author_sort | Hongxia Li |
| collection | DOAJ |
| description | ABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) is an established treatment for laterally spreading tumors (LSTs). Hybrid ESD, a novel technique, is gaining popularity for colorectal neoplasms. This study aimed to compare hybrid ESD with conventional ESD for treating LSTs. Methods Data from patients with colorectal LSTs ≥ 10 mm who underwent ESD at six centers from May 2020 to April 2023 were analyzed retrospectively. The study assessed baseline characteristics, hospitalization costs, and outcomes (operative time, R0 resection rate, complications). Results 890 patients were included: 490 underwent conventional ESD and 400 hybrid ESD. Hybrid ESD showed significantly shorter procedure times and lower hospitalization costs compared to conventional ESD. However, the R0 resection rate and lifting sign positivity were lower with hybrid ESD. Subgroup analysis indicated potential cost savings and shorter operative times for lesions 10–30 mm with hybrid ESD, without compromising R0 resection rates. For lesions ≥ 30 mm, hybrid ESD had lower R0 resection rates despite cost savings. Conclusion Hybrid ESD offers a viable alternative to conventional ESD for LSTs sized 10–30 mm, reducing procedure duration and costs while ensuring R0 resection. |
| format | Article |
| id | doaj-art-85c0ea4049054d0e84614daca83ad62f |
| institution | Kabale University |
| issn | 2397-9070 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | JGH Open |
| spelling | doaj-art-85c0ea4049054d0e84614daca83ad62f2024-12-30T04:16:37ZengWileyJGH Open2397-90702024-12-01812n/an/a10.1002/jgh3.70066Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter StudyHongxia Li0Yiping Hong1Linhua Yao2Xia Ji3Dan Chen4Maogen Tao5Huihui Yan6Jiamin Chen7Lingling Wang8Liyi Xu9Leilei Wang10Erfei Luo11Jianting Cai12Wei Wei13Department of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Affiliated Jinhua Hospital Zhejiang University School of Medicine Jinhua ChinaDepartment of Gastroenterology First Affiliated Hospital of Huzhou University Huzhou ChinaDepartment of Gastroenterology The Second Hospital of Jiaxing Jiaxing ChinaDepartment of Gastroenterology Jinhua People's Hospital Jinhua ChinaDepartment of Gastroenterology Lanxi People's Hospital Lanxi ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Clinical Nutrition, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Cardiology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine Zhejiang University Hangzhou ChinaABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) is an established treatment for laterally spreading tumors (LSTs). Hybrid ESD, a novel technique, is gaining popularity for colorectal neoplasms. This study aimed to compare hybrid ESD with conventional ESD for treating LSTs. Methods Data from patients with colorectal LSTs ≥ 10 mm who underwent ESD at six centers from May 2020 to April 2023 were analyzed retrospectively. The study assessed baseline characteristics, hospitalization costs, and outcomes (operative time, R0 resection rate, complications). Results 890 patients were included: 490 underwent conventional ESD and 400 hybrid ESD. Hybrid ESD showed significantly shorter procedure times and lower hospitalization costs compared to conventional ESD. However, the R0 resection rate and lifting sign positivity were lower with hybrid ESD. Subgroup analysis indicated potential cost savings and shorter operative times for lesions 10–30 mm with hybrid ESD, without compromising R0 resection rates. For lesions ≥ 30 mm, hybrid ESD had lower R0 resection rates despite cost savings. Conclusion Hybrid ESD offers a viable alternative to conventional ESD for LSTs sized 10–30 mm, reducing procedure duration and costs while ensuring R0 resection.https://doi.org/10.1002/jgh3.70066colorectal adenomaendoscopic submucosal dissectionhybrid endoscopic submucosal dissectionlaterally spreading tumors |
| spellingShingle | Hongxia Li Yiping Hong Linhua Yao Xia Ji Dan Chen Maogen Tao Huihui Yan Jiamin Chen Lingling Wang Liyi Xu Leilei Wang Erfei Luo Jianting Cai Wei Wei Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study JGH Open colorectal adenoma endoscopic submucosal dissection hybrid endoscopic submucosal dissection laterally spreading tumors |
| title | Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study |
| title_full | Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study |
| title_fullStr | Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study |
| title_full_unstemmed | Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study |
| title_short | Hybrid Versus Conventional Endoscopic Submucosal Dissection for Laterally Spreading Tumors (LSTs): A Retrospective Multicenter Study |
| title_sort | hybrid versus conventional endoscopic submucosal dissection for laterally spreading tumors lsts a retrospective multicenter study |
| topic | colorectal adenoma endoscopic submucosal dissection hybrid endoscopic submucosal dissection laterally spreading tumors |
| url | https://doi.org/10.1002/jgh3.70066 |
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