Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic
Introduction: Rotaviruses are the leading cause of severe diarrhea in infants and young children worldwide. To date, 32 distinct G genotypes and 47 distinct P genotypes have been identified in group A rotaviruses. Following the Coronavirus disease-2019 (COVID-19) pandemic, our country implemented se...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Turkish |
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Galenos Yayinevi
2024-11-01
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| Series: | Mediterranean Journal of Infection, Microbes and Antimicrobials |
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| Online Access: | https://mjima.org/articles/comparison-of-rotavirus-genotypes-before-and-during-the-covid-19-pandemic/doi/mjima.galenos.2024.24243.18 |
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| _version_ | 1846157244093169664 |
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| author | Ayşe ALICI Elif Seren TANRIVERDİ İlayda BUDAK Murat AKKAN Gülgün YENİŞEHİRLİ Barış OTLU |
| author_facet | Ayşe ALICI Elif Seren TANRIVERDİ İlayda BUDAK Murat AKKAN Gülgün YENİŞEHİRLİ Barış OTLU |
| author_sort | Ayşe ALICI |
| collection | DOAJ |
| description | Introduction: Rotaviruses are the leading cause of severe diarrhea in infants and young children worldwide. To date, 32 distinct G genotypes and 47 distinct P genotypes have been identified in group A rotaviruses. Following the Coronavirus disease-2019 (COVID-19) pandemic, our country implemented several measures that effectively reduced the incidence of infectious diseases, including acute gastroenteritis associated with COVID-19. In this study, we investigate whether the measures implemented following the COVID-19 pandemic led to changes in the rotavirus genotype distribution.
Materials and Methods: A total of 128 stool samples that tested positive for rotavirus antigen - 64 from the pre-pandemic period and 64 from the pandemic period - were further analyzed for genotyping. As determined by reverse transcription-polymerase chain reaction, rotavirus RNA was detected in 50 (78%) samples from the pre-pandemic period and 51 (80%) samples from the pandemic period.
Results: In the pre-pandemic period, the following results were observed among the patients studied by us: G9P[8] in 24 (48%), G1P[8] in 14 (28%), G2P[8] in five (10%), G2P[4] in three (6%), G3P[8] in two (4%), G4P[8] in one (2%), and G9P[4] in one (2%). During the pandemic period, the following results were observed in the patients studied by us: G9P[8] in 28 (54%), G1P[8] in 12 (24%), G2P[8] in six (12%), G2P[4] in two (4%), G3P[8] in one (2%), G4P[8] in one (2%), and G9P[4] in one (2%).
Conclusion: In our study, G9P[8] was the dominant genotype during both periods, showing no significant difference in rotavirus genotypes between the pre-pandemic and pandemic periods. |
| format | Article |
| id | doaj-art-852b77358f6f4616853baf2ad3f3e600 |
| institution | Kabale University |
| issn | 2147-673X |
| language | Turkish |
| publishDate | 2024-11-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Mediterranean Journal of Infection, Microbes and Antimicrobials |
| spelling | doaj-art-852b77358f6f4616853baf2ad3f3e6002024-11-25T12:43:36ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2024-11-01131181810.4274/mjima.galenos.2024.24243.18Comparison of Rotavirus Genotypes Before and During the COVID-19 PandemicAyşe ALICI0https://orcid.org/0000-0003-3709-1332Elif Seren TANRIVERDİ1https://orcid.org/0000-0002-0449-0356İlayda BUDAK2https://orcid.org/0009-0004-3681-859XMurat AKKAN3https://orcid.org/0000-0003-0020-1171Gülgün YENİŞEHİRLİ4https://orcid.org/0000-0001-7030-0752Barış OTLU5https://orcid.org/0000-0002-6220-0521Tavşanlı Doç. Dr. Mustafa Kalemli State Hospital, Clinic of Medical Microbiology, Kütahya, TurkeyMalatya Training and Research Hospital, Clinic of Medical Microbiology, Malatya, TurkeyTokat Gaziosmanpaşa University Faculty of Medicine, Department of Medical Microbiology, Tokat, TurkeyTokat Gaziosmanpaşa University Faculty of Medicine, Department of Medical Microbiology, Tokat, TurkeyTokat Gaziosmanpaşa University Faculty of Medicine, Department of Medical Microbiology, Tokat, Turkeyİnönü University Faculty of Medicine, Department of Medical Microbiology, Malatya, TurkeyIntroduction: Rotaviruses are the leading cause of severe diarrhea in infants and young children worldwide. To date, 32 distinct G genotypes and 47 distinct P genotypes have been identified in group A rotaviruses. Following the Coronavirus disease-2019 (COVID-19) pandemic, our country implemented several measures that effectively reduced the incidence of infectious diseases, including acute gastroenteritis associated with COVID-19. In this study, we investigate whether the measures implemented following the COVID-19 pandemic led to changes in the rotavirus genotype distribution. Materials and Methods: A total of 128 stool samples that tested positive for rotavirus antigen - 64 from the pre-pandemic period and 64 from the pandemic period - were further analyzed for genotyping. As determined by reverse transcription-polymerase chain reaction, rotavirus RNA was detected in 50 (78%) samples from the pre-pandemic period and 51 (80%) samples from the pandemic period. Results: In the pre-pandemic period, the following results were observed among the patients studied by us: G9P[8] in 24 (48%), G1P[8] in 14 (28%), G2P[8] in five (10%), G2P[4] in three (6%), G3P[8] in two (4%), G4P[8] in one (2%), and G9P[4] in one (2%). During the pandemic period, the following results were observed in the patients studied by us: G9P[8] in 28 (54%), G1P[8] in 12 (24%), G2P[8] in six (12%), G2P[4] in two (4%), G3P[8] in one (2%), G4P[8] in one (2%), and G9P[4] in one (2%). Conclusion: In our study, G9P[8] was the dominant genotype during both periods, showing no significant difference in rotavirus genotypes between the pre-pandemic and pandemic periods.https://mjima.org/articles/comparison-of-rotavirus-genotypes-before-and-during-the-covid-19-pandemic/doi/mjima.galenos.2024.24243.18covid-19 pandemicrotavirusgenotype |
| spellingShingle | Ayşe ALICI Elif Seren TANRIVERDİ İlayda BUDAK Murat AKKAN Gülgün YENİŞEHİRLİ Barış OTLU Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic Mediterranean Journal of Infection, Microbes and Antimicrobials covid-19 pandemic rotavirus genotype |
| title | Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic |
| title_full | Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic |
| title_fullStr | Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic |
| title_full_unstemmed | Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic |
| title_short | Comparison of Rotavirus Genotypes Before and During the COVID-19 Pandemic |
| title_sort | comparison of rotavirus genotypes before and during the covid 19 pandemic |
| topic | covid-19 pandemic rotavirus genotype |
| url | https://mjima.org/articles/comparison-of-rotavirus-genotypes-before-and-during-the-covid-19-pandemic/doi/mjima.galenos.2024.24243.18 |
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