The Photoprotective Effect of Curcumin on Skin Exposed to Ultraviolet Radiation

Introduction: Curcumin is an active ingredient mainly found in the Curcuma species’ rhizomes. It is a phenol with biological effects, such as anti-inflammatory, antioxidant, antimicrobial, wound healing, and antineoplastic. This paper aims to provide a systematic review of the literature on the phot...

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Main Authors: Aletheia Threskeia, Siti Khaerunnisa, Ahmad K. Al-Khazaleh, Indri Safitri Mukono
Format: Article
Language:English
Published: Wolters Kluwer – Medknow Publications 2024-12-01
Series:Biomolecular and Health Science Journal
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Online Access:https://journals.lww.com/10.4103/bhsj.bhsj_19_24
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Summary:Introduction: Curcumin is an active ingredient mainly found in the Curcuma species’ rhizomes. It is a phenol with biological effects, such as anti-inflammatory, antioxidant, antimicrobial, wound healing, and antineoplastic. This paper aims to provide a systematic review of the literature on the photoprotective effect of curcumin on skin irradiated by ultraviolet (UV) light (in vivo studies). Methods: This systematic review was done in compliance with PRISMA guidelines. We searched articles from Science Direct, Web of Science, Scopus, and PUBMED databases using specific search strategies. Results: Of the 805 articles identified, nine articles met the inclusion criteria. Curcumin, given orally or topically, was found to have a photoprotective effect on UV-exposed skin. Researchers found that curcumin protects against oxidants, reduces inflammation, prevents aging due to UV exposure, reduces epidermal thickness, reduces wrinkles, decreases inflammatory cytokines, and increases collagen density. Administration of curcumin in its pure form or from the extraction of Curcuma species showed similar good results. Conclusion: These review results show that curcumin can be an effective photoprotective compound used on UV-irradiated skin. Therefore, curcumin usage as an adjuvant along with sunscreen and other cosmetic products should be considered.
ISSN:2620-8636