Simple renal cysts and bovine aortic arch: markers for aortic disease
Objective This study aimed to assess the prevalence of thoracic aortic disease (TAD) and abdominal aortic aneurysms (AAA) among patients with simple renal cyst (SRC) and bovine aortic arch (BAA).Methods Through a retrospective search for patients who underwent both chest and abdominal CT imaging at...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2019-01-01
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| Series: | Open Heart |
| Online Access: | https://openheart.bmj.com/content/6/1/e000862.full |
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| author | Adam J Brownstein Syed Usman Bin Mahmood Ayman Saeyeldin Camilo Velasquez Mejia Mohammad A Zafar Yupeng Li John A Rizzo Neera K Dahl Young Erben Bulat A Ziganshin John A Elefteriades |
| author_facet | Adam J Brownstein Syed Usman Bin Mahmood Ayman Saeyeldin Camilo Velasquez Mejia Mohammad A Zafar Yupeng Li John A Rizzo Neera K Dahl Young Erben Bulat A Ziganshin John A Elefteriades |
| author_sort | Adam J Brownstein |
| collection | DOAJ |
| description | Objective This study aimed to assess the prevalence of thoracic aortic disease (TAD) and abdominal aortic aneurysms (AAA) among patients with simple renal cyst (SRC) and bovine aortic arch (BAA).Methods Through a retrospective search for patients who underwent both chest and abdominal CT imaging at our institution from 2012 to 2016, we identified patients with SRC and BAA and propensity score matched them to those without these features by age, gender and presence of hypertension, hyperlipidaemia, diabetes and chronic kidney disease.Results Of a total of 35 498 patients, 6366 were found to have SRC. Compared with the matched population without SRC, individuals with SRC were significantly more likely to have TAD (10.1% vs 3.9%), ascending aortic aneurysm (8.0% vs 3.2%), descending aortic aneurysm (3.3% vs 0.9%), type A aortic dissection (0.6% vs 0.2%), type B aortic dissection (1.1% vs 0.3%) and AAA (7.9% vs 3.3%). The 920 patients identified with BAA were significantly more likely to have TAD (21.8% vs 4.5%), ascending aortic aneurysm (18.4% vs 3.2%), descending aortic aneurysm (6.5% vs 2.0%), type A aortic dissection (1.4% vs 0.4%) and type B aortic dissection (2.4% vs 0.7%) than the matched population without BAA. SRC and BAA were found to be significantly associated with the presence of TAD (OR=2.57 and 7.69, respectively) and AAA (OR=2.81 and 2.56, respectively) on multivariable analysis.Conclusions This study establishes a substantial increased prevalence of aortic disease among patients with SRC and BAA. SRC and BAA should be considered markers for aortic aneurysm development. |
| format | Article |
| id | doaj-art-84c8ba8ba41d4f4ea42b96c84e630a14 |
| institution | Kabale University |
| issn | 2053-3624 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Open Heart |
| spelling | doaj-art-84c8ba8ba41d4f4ea42b96c84e630a142024-11-15T14:30:20ZengBMJ Publishing GroupOpen Heart2053-36242019-01-016110.1136/openhrt-2018-000862Simple renal cysts and bovine aortic arch: markers for aortic diseaseAdam J Brownstein0Syed Usman Bin Mahmood1Ayman Saeyeldin2Camilo Velasquez Mejia3Mohammad A Zafar4Yupeng Li5John A Rizzo6Neera K Dahl7Young Erben8Bulat A Ziganshin9John A Elefteriades102 Department of Medicine, Johns Hopkins Hospital and Johns Hopkins School of Medicine, Baltimore, MD, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA3 Department of Political Science and Economics, Rowan University, Glassboro, New Jersey, USA5 Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, New York, USA6 Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA1 Division of Vascular and Endovascular Surgery, Mayo Clinic in Florida, Jacksonville, Florida, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA1 Aortic Institute at Yale-New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USAObjective This study aimed to assess the prevalence of thoracic aortic disease (TAD) and abdominal aortic aneurysms (AAA) among patients with simple renal cyst (SRC) and bovine aortic arch (BAA).Methods Through a retrospective search for patients who underwent both chest and abdominal CT imaging at our institution from 2012 to 2016, we identified patients with SRC and BAA and propensity score matched them to those without these features by age, gender and presence of hypertension, hyperlipidaemia, diabetes and chronic kidney disease.Results Of a total of 35 498 patients, 6366 were found to have SRC. Compared with the matched population without SRC, individuals with SRC were significantly more likely to have TAD (10.1% vs 3.9%), ascending aortic aneurysm (8.0% vs 3.2%), descending aortic aneurysm (3.3% vs 0.9%), type A aortic dissection (0.6% vs 0.2%), type B aortic dissection (1.1% vs 0.3%) and AAA (7.9% vs 3.3%). The 920 patients identified with BAA were significantly more likely to have TAD (21.8% vs 4.5%), ascending aortic aneurysm (18.4% vs 3.2%), descending aortic aneurysm (6.5% vs 2.0%), type A aortic dissection (1.4% vs 0.4%) and type B aortic dissection (2.4% vs 0.7%) than the matched population without BAA. SRC and BAA were found to be significantly associated with the presence of TAD (OR=2.57 and 7.69, respectively) and AAA (OR=2.81 and 2.56, respectively) on multivariable analysis.Conclusions This study establishes a substantial increased prevalence of aortic disease among patients with SRC and BAA. SRC and BAA should be considered markers for aortic aneurysm development.https://openheart.bmj.com/content/6/1/e000862.full |
| spellingShingle | Adam J Brownstein Syed Usman Bin Mahmood Ayman Saeyeldin Camilo Velasquez Mejia Mohammad A Zafar Yupeng Li John A Rizzo Neera K Dahl Young Erben Bulat A Ziganshin John A Elefteriades Simple renal cysts and bovine aortic arch: markers for aortic disease Open Heart |
| title | Simple renal cysts and bovine aortic arch: markers for aortic disease |
| title_full | Simple renal cysts and bovine aortic arch: markers for aortic disease |
| title_fullStr | Simple renal cysts and bovine aortic arch: markers for aortic disease |
| title_full_unstemmed | Simple renal cysts and bovine aortic arch: markers for aortic disease |
| title_short | Simple renal cysts and bovine aortic arch: markers for aortic disease |
| title_sort | simple renal cysts and bovine aortic arch markers for aortic disease |
| url | https://openheart.bmj.com/content/6/1/e000862.full |
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