PPB-Affinity: Protein-Protein Binding Affinity dataset for AI-based protein drug discovery

PPB-Affinity: Protein-Protein Binding Affinity dataset for AI-based protein drug discovery

Abstract Prediction of protein-protein binding (PPB) affinity plays an important role in large-molecular drug discovery. Deep learning (DL) has been adopted to predict the changes of PPB binding affinities upon mutations, but there was a scarcity of studies predicting the PPB affinity itself. The ma...

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Bibliographic Details
Main Authors: Huaqing Liu, Peiyi Chen, Xiaochen Zhai, Ku-Geng Huo, Shuxian Zhou, Lanqing Han, Guoxin Fan
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-024-03997-4
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