PLCG2 promotes hepatocyte proliferation in vitro via NF-κB and ERK pathway by targeting bcl2, myc and ccnd1
Phospholipase Cγ2 (PLCG2) has been implicated in the regulation of cell proliferation, transformation, and tumor growth. In this study, we investigate the mechanism of PLCG2 action using a short interference RNA (siRNA) method. The effects of PLCG2 on rat liver BRL-3A cells treated siRNA were studie...
Saved in:
| Main Authors: | Donghui Ma, Fang Lian, Xiaobai Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2019-12-01
|
| Series: | Artificial Cells, Nanomedicine, and Biotechnology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21691401.2019.1669616 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Reduced PLCG1 expression is associated with inferior survival for myelodysplastic syndromes
by: Masayuki Shiseki, et al.
Published: (2020-01-01) -
mRNA turnover rate limits siRNA and microRNA efficacy
by: Erik Larsson, et al.
Published: (2010-11-01) -
Aptamer–ODN Chimeras: Enabling Cell-Specific ODN Targeting Therapy
by: Bei Xia, et al.
Published: (2025-05-01) -
Target mRNA abundance dilutes microRNA and siRNA activity
by: Aaron Arvey, et al.
Published: (2010-04-01) -
Harnessing RNA therapeutics: novel approaches and emerging strategies for cardiovascular disease management
by: Wang Dui, et al.
Published: (2025-03-01)