In vitro colonic fermentation of fermented Radix Astragali by Poria cocos and anti-hyperuricemia mechanism based on network pharmacology and experiment verification

In vitro colonic fermentation of fermented Radix Astragali by Poria cocos and anti-hyperuricemia mechanism based on network pharmacology and experiment verification

AimThis research aimed to probe the effects of fecal microbiota and Lactobacillus acidophilus on the metabolism of Radix Astragali (RA) and Poria cocos solid fermenting Radix Astragali (FRA). It further explores pharmacological effects of RA, Poria cocos, and FRA on HUA mouse model and the mechanism...

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Bibliographic Details
Main Authors: Caiyun Chen, Keyu Liu, Yishu Wang, Xinru Song, Wenjing Gao, Yanlin Wang, Yuxin Chen, Ziqi An, Changting Yin, Haiyan Wang, Shaoping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Nutrition
Subjects:
Radix Astragali
colonic fermentation
Lactobacillus acidophilus
hyperuricemia
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1466702/full
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