Succinylation modification-mediated upregulation of Sp1 promotes hepatocellular carcinoma cell proliferation

Succinylation modification-mediated upregulation of Sp1 promotes hepatocellular carcinoma cell proliferation

Abstract Hepatocellular carcinoma (HCC) remains one of the most prevalent malignant tumors globally, characterized by high incidence and mortality rates. Despite ongoing research, the underlying molecular mechanisms of HCC development are not yet fully understood. Utilizing bioinformatic analysis, r...

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Bibliographic Details
Main Authors: Yehong Han, Xueqin Deng, Haixia Chen, Jie Chen, Wei Xu, Lanqin Liu
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
Sp1
Succinylation
mTOR
KAT2A
Online Access:https://doi.org/10.1007/s12672-024-01533-9
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