The role of platelets in tumor immune evasion and metastasis: mechanisms and therapeutic implications

The role of platelets in tumor immune evasion and metastasis: mechanisms and therapeutic implications

Abstract Only circulating tumor cells (CTCs) that successfully evade immune surveillance upon entering the bloodstream can lead to clonal expansion and metastasis. Cancer progression is accompanied by pathophysiological processes such as platelet activation and thrombosis. Platelets secrete a variet...

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Bibliographic Details
Main Authors: Jiaqi Gan, Xinjun Zhang, Jie Guo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Platelet
CTC
Immune cell
Immune escape
Signaling pathway
Therapy
Online Access:https://doi.org/10.1186/s12935-025-03877-w
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