Exploring the causal relationship between chronic periodontitis and oral cancer: An insight

Oral carcinoma is a major public health concern worldwide due to its increasing mortality. Apart from alcohol consumption, tobacco and areca nut chewing, other risk factors for oral cancer include chronic infection and inflammation, poor nutritional status, chronic trauma to the oral soft tissues et...

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Main Authors: Shaswata Karmakar, Baishakhi Modak, Monica Charlotte Solomon
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Oral Oncology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024003145
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author Shaswata Karmakar
Baishakhi Modak
Monica Charlotte Solomon
author_facet Shaswata Karmakar
Baishakhi Modak
Monica Charlotte Solomon
author_sort Shaswata Karmakar
collection DOAJ
description Oral carcinoma is a major public health concern worldwide due to its increasing mortality. Apart from alcohol consumption, tobacco and areca nut chewing, other risk factors for oral cancer include chronic infection and inflammation, poor nutritional status, chronic trauma to the oral soft tissues etc. Risk of developing oral cancer increases with periodontal diseases. Induction of carcinoma by periodontal disease appears possible since the inflammatory mediators and bacterial toxins in the disease have a potential for malignant transformation. Establishing the etio-pathological connections between chronic periodontitis and oral carcinoma would be of great importance. Moreover, improvement of oral hygiene to prevent periodontal diseases also reduces the risks for cancer. These facts intensify the need for oral health education programs to educate individuals about the importance of maintaining a good oral hygiene for the early detection and prevention of oral cancer.
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series Oral Oncology Reports
spelling doaj-art-833f9896da2e43ffb7c0a1abdee18b322025-01-09T06:16:25ZengElsevierOral Oncology Reports2772-90602024-09-0111100468Exploring the causal relationship between chronic periodontitis and oral cancer: An insightShaswata Karmakar0Baishakhi Modak1Monica Charlotte Solomon2Department of Periodontology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, IndiaDepartment of oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, IndiaDepartment of oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India; Corresponding author. Department of oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.Oral carcinoma is a major public health concern worldwide due to its increasing mortality. Apart from alcohol consumption, tobacco and areca nut chewing, other risk factors for oral cancer include chronic infection and inflammation, poor nutritional status, chronic trauma to the oral soft tissues etc. Risk of developing oral cancer increases with periodontal diseases. Induction of carcinoma by periodontal disease appears possible since the inflammatory mediators and bacterial toxins in the disease have a potential for malignant transformation. Establishing the etio-pathological connections between chronic periodontitis and oral carcinoma would be of great importance. Moreover, improvement of oral hygiene to prevent periodontal diseases also reduces the risks for cancer. These facts intensify the need for oral health education programs to educate individuals about the importance of maintaining a good oral hygiene for the early detection and prevention of oral cancer.http://www.sciencedirect.com/science/article/pii/S2772906024003145Oral cancerPeriodontitisPoor oral hygieneInflammationPeriodontopathogens
spellingShingle Shaswata Karmakar
Baishakhi Modak
Monica Charlotte Solomon
Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
Oral Oncology Reports
Oral cancer
Periodontitis
Poor oral hygiene
Inflammation
Periodontopathogens
title Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
title_full Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
title_fullStr Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
title_full_unstemmed Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
title_short Exploring the causal relationship between chronic periodontitis and oral cancer: An insight
title_sort exploring the causal relationship between chronic periodontitis and oral cancer an insight
topic Oral cancer
Periodontitis
Poor oral hygiene
Inflammation
Periodontopathogens
url http://www.sciencedirect.com/science/article/pii/S2772906024003145
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