Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review
Experimental and clinical studies using cell therapy are very popular. Mesenchymal stem cells (MSCs) and stem cell-derived extracellular vesicles (EV) are used as one of the components of therapy in these researches. The action of MSCs is mediated by the release of EV which play a direct role in the...
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| Format: | Article |
| Language: | Russian |
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ZAO "Consilium Medicum"
2024-10-01
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| Series: | Consilium Medicum |
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| Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/352567/pdf |
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| _version_ | 1841527616989822976 |
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| author | Veronika V. Shumko Andrei I. Gorelov Anna N. Remezova Yanina G. Ivanova Alexandr N. Muraviov Natalia M. Yudintceva Tatiana I. Vinogradova Anna A. Gorelova |
| author_facet | Veronika V. Shumko Andrei I. Gorelov Anna N. Remezova Yanina G. Ivanova Alexandr N. Muraviov Natalia M. Yudintceva Tatiana I. Vinogradova Anna A. Gorelova |
| author_sort | Veronika V. Shumko |
| collection | DOAJ |
| description | Experimental and clinical studies using cell therapy are very popular. Mesenchymal stem cells (MSCs) and stem cell-derived extracellular vesicles (EV) are used as one of the components of therapy in these researches. The action of MSCs is mediated by the release of EV which play a direct role in the implementation of several important biological processes: angiogenesis, proliferation, modulation of the inflammatory process and immune response, inhibition of cellular apoptosis, etc. These properties of MSCs and stem cell-derived EV are of interest in the treatment of tuberculosis infection, because an integral part of the pathogenesis of tuberculosis is the creation of specific granulomas and the formation of fibrosis. |
| format | Article |
| id | doaj-art-82bcd68c1617489b83bbef65e59a7f1f |
| institution | Kabale University |
| issn | 2075-1753 2542-2170 |
| language | Russian |
| publishDate | 2024-10-01 |
| publisher | ZAO "Consilium Medicum" |
| record_format | Article |
| series | Consilium Medicum |
| spelling | doaj-art-82bcd68c1617489b83bbef65e59a7f1f2025-01-15T11:58:17ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702024-10-0126961161410.26442/20751753.2024.9.2026684869Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A reviewVeronika V. Shumko0https://orcid.org/0009-0008-6843-1145Andrei I. Gorelov1https://orcid.org/0000-0002-2858-5317Anna N. Remezova2https://orcid.org/0000-0001-8145-4159Yanina G. Ivanova3https://orcid.org/0000-0002-4885-8095Alexandr N. Muraviov4https://orcid.org/0000-0002-6974-5305Natalia M. Yudintceva5https://orcid.org/0000-0002-7357-1571Tatiana I. Vinogradova6https://orcid.org/0000-0002-5234-349XAnna A. Gorelova7https://orcid.org/0000-0002-7010-7562Saint Petersburg State Research Institute of PhthisiopulmonologySaint Petersburg State UniversitySaint Petersburg State Research Institute of PhthisiopulmonologySaint Petersburg State UniversitySaint Petersburg State Research Institute of PhthisiopulmonologyInstitute of Cytology of the Russian Academy of SciencesSaint Petersburg State Research Institute of PhthisiopulmonologySaint Petersburg State Research Institute of PhthisiopulmonologyExperimental and clinical studies using cell therapy are very popular. Mesenchymal stem cells (MSCs) and stem cell-derived extracellular vesicles (EV) are used as one of the components of therapy in these researches. The action of MSCs is mediated by the release of EV which play a direct role in the implementation of several important biological processes: angiogenesis, proliferation, modulation of the inflammatory process and immune response, inhibition of cellular apoptosis, etc. These properties of MSCs and stem cell-derived EV are of interest in the treatment of tuberculosis infection, because an integral part of the pathogenesis of tuberculosis is the creation of specific granulomas and the formation of fibrosis.https://consilium.orscience.ru/2075-1753/article/viewFile/352567/pdftuberculosisextracellular vesiclesmesenchymal stem cells |
| spellingShingle | Veronika V. Shumko Andrei I. Gorelov Anna N. Remezova Yanina G. Ivanova Alexandr N. Muraviov Natalia M. Yudintceva Tatiana I. Vinogradova Anna A. Gorelova Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review Consilium Medicum tuberculosis extracellular vesicles mesenchymal stem cells |
| title | Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review |
| title_full | Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review |
| title_fullStr | Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review |
| title_full_unstemmed | Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review |
| title_short | Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review |
| title_sort | therapeutic potential of mesenchymal stem cells and stem cell derived extracellular vesicles in tuberculosis of various localizations a review |
| topic | tuberculosis extracellular vesicles mesenchymal stem cells |
| url | https://consilium.orscience.ru/2075-1753/article/viewFile/352567/pdf |
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