Zhili decoction ameliorates ulcerative colitis by modulating gut microbiota and related metabolite, and inhibiting the TLR4/NF-κB/NLRP3 pathway

Zhili decoction ameliorates ulcerative colitis by modulating gut microbiota and related metabolite, and inhibiting the TLR4/NF-κB/NLRP3 pathway

Ethnopharmacological ImportanceZhili decoction (ZLD) is a traditional Chinese medicine prescription for ulcerative colitis (UC). However, the mechanism by which ZLD exerts its therapeutic effects in the context of UC remains unclear.Aim of studyThe aim of this study was to investigate the effects of...

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Bibliographic Details
Main Authors: Tianying Tan, Qin Chen, Ping Chen, Shuangshuang Li, Wenting Hu, Tao Yang, Yingtian Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
Zhili decoction
gut microbiome
metabolism
TLR4/NF-κB/NLRP3 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1481273/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1481273/full

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