Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human leptospirosis

Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human leptospirosis

Abstract Background Leptospirosis is a zoonotic bacterial infection occurring worldwide. It is of particular public health concern due to its global distribution, epidemic potential and high mortality without appropriate treatment. The method for the management of leptospirosis, particularly in seve...

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Bibliographic Details
Main Authors: Nathaniel Lee, Chris Smith, Robin Bailey, Koya Ariyoshi, Sarah Smith, Nick Black, Tansy Edwards
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Trials
Subjects:
Leptospirosis
Core outcome set
Clinical trial
Systematic review
Qualitative interview
Delphi survey
Online Access:https://doi.org/10.1186/s13063-024-08713-6
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