A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial
Abstract Alcohol use attenuates successful smoking cessation. We examined the feasibility, acceptability, and preliminary efficacy of a brief alcohol intervention in smokers. In this two-arm, assessor-blinded randomized controlled trial, we randomized 100 daily smokers (82.0% male, mean age = 43.7 y...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-83405-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841559544704008192 |
|---|---|
| author | Yee Tak Derek Cheung Tin Shun Titan Mak Tzu Tsun Luk Kam-wing Joe Ching Nga-ting Grace Wong Ching Han Helen Chan Man Ping Wang Tai Hing Lam |
| author_facet | Yee Tak Derek Cheung Tin Shun Titan Mak Tzu Tsun Luk Kam-wing Joe Ching Nga-ting Grace Wong Ching Han Helen Chan Man Ping Wang Tai Hing Lam |
| author_sort | Yee Tak Derek Cheung |
| collection | DOAJ |
| description | Abstract Alcohol use attenuates successful smoking cessation. We examined the feasibility, acceptability, and preliminary efficacy of a brief alcohol intervention in smokers. In this two-arm, assessor-blinded randomized controlled trial, we randomized 100 daily smokers (82.0% male, mean age = 43.7 years) with past-year alcohol use in smoking cessation clinics. Both intervention (n = 51) and control (n = 49) groups received conventional smoking cessation treatment, the intervention group additionally received a brief alcohol intervention. Primary outcome was biochemically validated tobacco abstinence at 2 months. Secondary outcomes included Alcohol Use Disorders Identification Test (AUDIT) scores, self-reported past 7-day alcohol consumption in alcohol units, feasibility, and acceptability scores at 2 months. By intention-to-treat, the intervention group showed higher validated abstinence (11.8% vs. 10.2%, Risk Ratio = 1.15, 95%CI = 0.38–3.53), lower AUDIT score (5.3 vs. 6.5), and lower alcohol consumption (5.6 vs. 7.1) than the control group, but the differences were not significant. Overall, the feasibility was high (4.2/5.0), and the acceptability was modest (5.0/7.0). In all participants, reduction in smoking relapse risk due to alcohol use from baseline to 2-month follow-up was associated with higher biochemically validated abstinence (Adjusted odds ratio: 1.55, 95% CI = 1.05–2.28). Our brief alcohol intervention is feasible, acceptable, and potentially efficacious to promote tobacco abstinence and alcohol reduction. |
| format | Article |
| id | doaj-art-8274fc321dd546fa8a3faa05fa6716ea |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-8274fc321dd546fa8a3faa05fa6716ea2025-01-05T12:24:45ZengNature PortfolioScientific Reports2045-23222024-12-0114111110.1038/s41598-024-83405-4A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trialYee Tak Derek Cheung0Tin Shun Titan Mak1Tzu Tsun Luk2Kam-wing Joe Ching3Nga-ting Grace Wong4Ching Han Helen Chan5Man Ping Wang6Tai Hing Lam7School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong KongSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong KongSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong KongIntegrated Centre on Smoking Cessation, Tung Wah Group of HospitalsIntegrated Centre on Smoking Cessation, Tung Wah Group of HospitalsIntegrated Centre on Smoking Cessation, Tung Wah Group of HospitalsSchool of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong KongSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong KongAbstract Alcohol use attenuates successful smoking cessation. We examined the feasibility, acceptability, and preliminary efficacy of a brief alcohol intervention in smokers. In this two-arm, assessor-blinded randomized controlled trial, we randomized 100 daily smokers (82.0% male, mean age = 43.7 years) with past-year alcohol use in smoking cessation clinics. Both intervention (n = 51) and control (n = 49) groups received conventional smoking cessation treatment, the intervention group additionally received a brief alcohol intervention. Primary outcome was biochemically validated tobacco abstinence at 2 months. Secondary outcomes included Alcohol Use Disorders Identification Test (AUDIT) scores, self-reported past 7-day alcohol consumption in alcohol units, feasibility, and acceptability scores at 2 months. By intention-to-treat, the intervention group showed higher validated abstinence (11.8% vs. 10.2%, Risk Ratio = 1.15, 95%CI = 0.38–3.53), lower AUDIT score (5.3 vs. 6.5), and lower alcohol consumption (5.6 vs. 7.1) than the control group, but the differences were not significant. Overall, the feasibility was high (4.2/5.0), and the acceptability was modest (5.0/7.0). In all participants, reduction in smoking relapse risk due to alcohol use from baseline to 2-month follow-up was associated with higher biochemically validated abstinence (Adjusted odds ratio: 1.55, 95% CI = 1.05–2.28). Our brief alcohol intervention is feasible, acceptable, and potentially efficacious to promote tobacco abstinence and alcohol reduction.https://doi.org/10.1038/s41598-024-83405-4Smoking cessationAlcoholDrinkingBrief alcohol interventionCo-use of tobacco and alcohol |
| spellingShingle | Yee Tak Derek Cheung Tin Shun Titan Mak Tzu Tsun Luk Kam-wing Joe Ching Nga-ting Grace Wong Ching Han Helen Chan Man Ping Wang Tai Hing Lam A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial Scientific Reports Smoking cessation Alcohol Drinking Brief alcohol intervention Co-use of tobacco and alcohol |
| title | A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial |
| title_full | A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial |
| title_fullStr | A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial |
| title_full_unstemmed | A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial |
| title_short | A brief alcohol intervention during smoking cessation treatment in daily cigarette smokers: A pilot randomized controlled trial |
| title_sort | brief alcohol intervention during smoking cessation treatment in daily cigarette smokers a pilot randomized controlled trial |
| topic | Smoking cessation Alcohol Drinking Brief alcohol intervention Co-use of tobacco and alcohol |
| url | https://doi.org/10.1038/s41598-024-83405-4 |
| work_keys_str_mv | AT yeetakderekcheung abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT tinshuntitanmak abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT tzutsunluk abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT kamwingjoeching abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT ngatinggracewong abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT chinghanhelenchan abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT manpingwang abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT taihinglam abriefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT yeetakderekcheung briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT tinshuntitanmak briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT tzutsunluk briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT kamwingjoeching briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT ngatinggracewong briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT chinghanhelenchan briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT manpingwang briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial AT taihinglam briefalcoholinterventionduringsmokingcessationtreatmentindailycigarettesmokersapilotrandomizedcontrolledtrial |