Colonic Aging and Colorectal Cancer: An Unignorable Interplay and Its Translational Implications

Colonic Aging and Colorectal Cancer: An Unignorable Interplay and Its Translational Implications

Colorectal cancer (CRC) incidence increases markedly with age, yet chronological age is an inadequate proxy for the complex biological processes involved. Colon aging, the intrinsic biological aging of the colonic tissue, is emerging as a crucial, active driver of CRC development. This review compre...

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Bibliographic Details
Main Authors: Qiyan Yin, Fen Qin, Fangliu Gan, Guangxi Zhao, Ronghua Chen, Yue Wen, Xueyang Hua, Fugui Zeng, Yuezheng Zhang, Yuliang Xiao, Wenbing Xie, Yong Tao
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biology
Subjects:
colon aging
colorectal cancer
biological aging
microenvironment
inflammation
dysbiosis
Online Access:https://www.mdpi.com/2079-7737/14/7/805
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