Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulation

Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulation

Abstract Anchusa italica Retz. (AIR), a traditional herbal remedy, is commonly applied in managing heart and brain disorders. However, its specific function and mechanism in acute cerebral ischemia–reperfusion injury (CIRI) are not fully understood. This research focused on the interventional effect...

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Bibliographic Details
Main Authors: Wenta Tan, Shuo Fu, Yufei Wang, Bojun Hu, Guiquan Ding, Li Zhang, Wen Zhang, Guanhua Du, Junke Song
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Natural Products and Bioprospecting
Subjects:
Anchusa italica Retz.
Cerebral ischemia–reperfusion injury
Transcriptomics
Metabolomics
Wnt/β-catenin signaling pathway
Online Access:https://doi.org/10.1007/s13659-024-00495-3
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