Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions
Coronary restenosis remains the main problem for effectiveness of percutaneous transluminal coronary angioplasty (PCA) and coronary stenting (CS). The aim of this review is to analyze pathogenetic mechanisms of coronary restenosis after PCA and CS, as well as various polymorphisms of relevant candid...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2007-10-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1386 |
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| author | Yu. A. Shuvalova A. N. Meshkov A. I. Kaminny G. F. Piksina V. V. Kukharchuk |
| author_facet | Yu. A. Shuvalova A. N. Meshkov A. I. Kaminny G. F. Piksina V. V. Kukharchuk |
| author_sort | Yu. A. Shuvalova |
| collection | DOAJ |
| description | Coronary restenosis remains the main problem for effectiveness of percutaneous transluminal coronary angioplasty (PCA) and coronary stenting (CS). The aim of this review is to analyze pathogenetic mechanisms of coronary restenosis after PCA and CS, as well as various polymorphisms of relevant candidate genes as potential genetic markers of post‑PCA and post‑CS restenosis. Both pathophysiological mechanisms and genetic basis are different for stent restenosis and post‑PCA, stent‑free restenosis. There are genes, which could be used as genetic markers of stent restenosis risk. For PCA restenosis risk, there are genes, also used as genetic markers. Genetic testing before percutaneous coronary interventions could identify patients with high restenosis risk, that, combined with new pharmaceutical approaches, will decrease coronary restenosis rates after PCA and CS. |
| format | Article |
| id | doaj-art-81df1b177ef942d282a1500a2cbd87db |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2007-10-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-81df1b177ef942d282a1500a2cbd87db2025-08-20T03:57:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-10-01651071141096Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventionsYu. A. Shuvalova0A. N. Meshkov1A. I. Kaminny2G. F. Piksina3V. V. Kukharchuk4Russian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development, MoscowRussian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development, MoscowRussian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development, MoscowRussian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development, MoscowRussian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development, MoscowCoronary restenosis remains the main problem for effectiveness of percutaneous transluminal coronary angioplasty (PCA) and coronary stenting (CS). The aim of this review is to analyze pathogenetic mechanisms of coronary restenosis after PCA and CS, as well as various polymorphisms of relevant candidate genes as potential genetic markers of post‑PCA and post‑CS restenosis. Both pathophysiological mechanisms and genetic basis are different for stent restenosis and post‑PCA, stent‑free restenosis. There are genes, which could be used as genetic markers of stent restenosis risk. For PCA restenosis risk, there are genes, also used as genetic markers. Genetic testing before percutaneous coronary interventions could identify patients with high restenosis risk, that, combined with new pharmaceutical approaches, will decrease coronary restenosis rates after PCA and CS.https://cardiovascular.elpub.ru/jour/article/view/1386gene polymorphismspercutaneous transluminal balloon angioplastycoronary stentingrestenosis |
| spellingShingle | Yu. A. Shuvalova A. N. Meshkov A. I. Kaminny G. F. Piksina V. V. Kukharchuk Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions Кардиоваскулярная терапия и профилактика gene polymorphisms percutaneous transluminal balloon angioplasty coronary stenting restenosis |
| title | Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| title_full | Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| title_fullStr | Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| title_full_unstemmed | Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| title_short | Restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| title_sort | restenosis pathophysiological mechanisms and genetic markers after percutaneous coronary interventions |
| topic | gene polymorphisms percutaneous transluminal balloon angioplasty coronary stenting restenosis |
| url | https://cardiovascular.elpub.ru/jour/article/view/1386 |
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