Chromatin landscape dynamics during reprogramming towards human naïve and primed pluripotency reveals the divergent function of PRDM1 isoforms

Chromatin landscape dynamics during reprogramming towards human naïve and primed pluripotency reveals the divergent function of PRDM1 isoforms

Abstract Induced pluripotent stem cells (iPSCs) technology holds great potential in both scientific research and clinical applications. It enables the generation of naïve and primed iPSCs from various cell types through different strategies. Despite extensive characterizations of transcriptional and...

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Main Authors: Jianfeng Zhou, Mingyue Guo, Guang Yang, Xinyu Cui, Jindian Hu, Tan Lin, Hong Wang, Shaorong Gao, Cizhong Jiang, Liping Wang, Yixuan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02230-w
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https://doi.org/10.1038/s41420-024-02230-w

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