Characterization of NOD-like receptor-based molecular heterogeneity in glioma and its association with immune micro-environment and metabolism reprogramming

Characterization of NOD-like receptor-based molecular heterogeneity in glioma and its association with immune micro-environment and metabolism reprogramming

Background and purposeThe characteristics and role of NOD-like receptor (NLR) signaling pathway in high-grade gliomas were still unclear. This study aimed to reveal the association of NLR with clinical heterogeneity of glioblastoma (GBM) patients, and to explore the role of NLR pathway hub genes in...

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Bibliographic Details
Main Authors: Chunlin Lu, Huihao Ma, Jie Wang, Fei Sun, Mingyang Fei, Ying Li, Jing Liu, Bin Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
NLR pathway
GBM
immune microenvironment
metabolism reprogramming
clinical heterogeneity
TRIP6
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1498583/full
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