The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19

Background/aims: The covid-19 pandemic, which is a global problem, is still one of the most important health problems today. Treatment and vaccine studies are as important in predicting prognosis and mortality as early diagnosis and prevention of the disease, which continues unabated. İn this study,...

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Main Authors: Öznur Köylü, Ramazan Köylü, Muhammet Ali Erinmez
Format: Article
Language:English
Published: Selcuk University Press 2024-04-01
Series:Genel Tıp Dergisi
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Online Access:https://dergipark.org.tr/tr/download/article-file/3477336
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author Öznur Köylü
Ramazan Köylü
Muhammet Ali Erinmez
author_facet Öznur Köylü
Ramazan Köylü
Muhammet Ali Erinmez
author_sort Öznur Köylü
collection DOAJ
description Background/aims: The covid-19 pandemic, which is a global problem, is still one of the most important health problems today. Treatment and vaccine studies are as important in predicting prognosis and mortality as early diagnosis and prevention of the disease, which continues unabated. İn this study, it was aimed to evaluate the success of laboratory values, comorbid conditions and intensive care scoring at the time of first admission of patients admitted to intensive care with the diagnosis of Covid-19 in predicting mortality. Methods: The study was conducted in a 3rd step adult emergency deparment. The study included 106 patients who were admitted to the emergency department and subsequently admitted to intensive care, had a positive Covid-19 polymerase chain reaction(PCR) test and met the inclusion criteria. Results: The average age of 10 patients included in the study was 71.85. 65.09 percent of these patients are male and 24.1% are female. While 29 of the patients were survivors, 77 were deceased. İn deceased patients; Procalcitonin, lactate, leukocyte, neutrophil, urea, creatine, asti crpi ferritin, d-dimer values were found to be higher than the other group. Lymphocyte, lymphocyte percentage and pH values were found to be significantly low. Sequential Organ Failure Score(SOFA) and Acute Physiology and Chronic Health Evaluation(APACHE) 2 scores were found to be higher in deceased patients. Conclusion: Ferritin, lactate, urea and pH values, comorbid conditions, Sequantial Organ Failure Score and Acute Sphysiology and Chronic Health Assessment 2 can be used to predict mortality in covid-19 disease.
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publishDate 2024-04-01
publisher Selcuk University Press
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series Genel Tıp Dergisi
spelling doaj-art-813300b006624d0aa81fb6e9f7d1b3da2025-01-03T00:46:52ZengSelcuk University PressGenel Tıp Dergisi2602-37412024-04-0134221822210.54005/geneltip.1376569154The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19Öznur Köylü0Ramazan Köylü1Muhammet Ali Erinmez2Konya Şehir HastanesiKonya Şehir Hastanesimersin şehir hastanesiBackground/aims: The covid-19 pandemic, which is a global problem, is still one of the most important health problems today. Treatment and vaccine studies are as important in predicting prognosis and mortality as early diagnosis and prevention of the disease, which continues unabated. İn this study, it was aimed to evaluate the success of laboratory values, comorbid conditions and intensive care scoring at the time of first admission of patients admitted to intensive care with the diagnosis of Covid-19 in predicting mortality. Methods: The study was conducted in a 3rd step adult emergency deparment. The study included 106 patients who were admitted to the emergency department and subsequently admitted to intensive care, had a positive Covid-19 polymerase chain reaction(PCR) test and met the inclusion criteria. Results: The average age of 10 patients included in the study was 71.85. 65.09 percent of these patients are male and 24.1% are female. While 29 of the patients were survivors, 77 were deceased. İn deceased patients; Procalcitonin, lactate, leukocyte, neutrophil, urea, creatine, asti crpi ferritin, d-dimer values were found to be higher than the other group. Lymphocyte, lymphocyte percentage and pH values were found to be significantly low. Sequential Organ Failure Score(SOFA) and Acute Physiology and Chronic Health Evaluation(APACHE) 2 scores were found to be higher in deceased patients. Conclusion: Ferritin, lactate, urea and pH values, comorbid conditions, Sequantial Organ Failure Score and Acute Sphysiology and Chronic Health Assessment 2 can be used to predict mortality in covid-19 disease.https://dergipark.org.tr/tr/download/article-file/3477336covid-19crpd-dimerferritinfibrinogencovid-19crpd-dimerferritinfibrinojen
spellingShingle Öznur Köylü
Ramazan Köylü
Muhammet Ali Erinmez
The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
Genel Tıp Dergisi
covid-19
crp
d-dimer
ferritin
fibrinogen
covid-19
crp
d-dimer
ferritin
fibrinojen
title The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
title_full The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
title_fullStr The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
title_full_unstemmed The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
title_short The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19
title_sort relationship between acute phase reactants levels at the time of admission and comorbid conditions with mortality in patients diagnosed with covid 19
topic covid-19
crp
d-dimer
ferritin
fibrinogen
covid-19
crp
d-dimer
ferritin
fibrinojen
url https://dergipark.org.tr/tr/download/article-file/3477336
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