A germline FLT3 variant in aplastic anemia
Abstract FMS-like tyrosine kinase 3 (FLT3) genetic variants are commonly seen in high-grade myeloid neoplasms and are typically gain-of-function mutations associated with a proliferative disease phenotype. Inactivating FLT3 variants have been less frequently described in non-malignant, autoimmune di...
Saved in:
Main Authors: | Lemchukwu C. Amaeshi, Amalia A. Sofianidi, Aditi Shastri, Mendel Goldfinger, Marina Konopleva, Amit K. Verma, Mark Chaitowitz, Ioannis Mantzaris |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
|
Series: | Biomarker Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40364-024-00717-3 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Clinical utility of hematological parameters in aplastic anemia
by: Lizhong Zhang, et al.
Published: (2025-01-01) -
Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000
by: Aleksandar M. Kostov, et al.
Published: (2025-01-01) -
COEXISTENCE OF MULTIPLE GENE VARIANTS IN SOME PATIENTS WITH ERYTHROCYTOSES
by: Andrea Benetti, et al.
Published: (2024-02-01) -
Personalized screening strategies for TP53 R337H carriers: a retrospective cohort study of tumor spectrum in Li-Fraumeni syndrome adult carriersResearch in context
by: Pedro A.F. Galante, et al.
Published: (2025-02-01) -
Nanopore adaptive sampling accurately detects nucleotide variants and improves the characterization of large‐scale rearrangement for the diagnosis of cancer predisposition
by: Sandy Chevrier, et al.
Published: (2025-01-01)